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Bruce Russell
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Professor of Parasitology
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About
Dr. Bruce Russell is an Associate Professor at the University of Otago, New Zealand. His research focuses on the functional and immunological mapping of malaria-related proteins, gastrointestinal microbiome interactions, and the pharmacological profiles of novel antimalarial compounds. He has contributed significantly to the understanding of erythrocyte tropism in malaria and the genetic diversity of Plasmodium vivax . His recent articles reflect an extensive study on malaria mechanisms, emphasizing the importance of both host-parasite interactions and microbiome dynamics.
Recent Grants
Grant: Close
Leveraging neuropharmacology to target trap-shy and bait-shy vertebrate pests
Open Date: 2022-10-01
Close Date: 2025-09-30
Grant: Close
Walking backwards into the future: An evolutionary investigation into the high rates of metabolic disease in Pacific populations
Open Date: 2020-01-01
Close Date: 2023-01-01
Grant: Close
Unraveling the molecular basis for vivax malaria's unhealthy attraction to human reticulocytes
Open Date: 2018-01-01
Close Date: 2021-01-01
Grant: Close
Genetic and molecular basis of drug resistance and drug action in vivax malaria
Open Date: 2017-01-01
Close Date: 2020-10-01
Grant: Close
Plasmodium vivax culutre and its application to understanding the biology of chloroquine resistance
Open Date: 2005-01-01
Close Date: 2006-12-31
Articles (16)
Year:
2026
Year:
2025
Testing Plasmodium vivax antimicrobial sensitivity is limited to ex vivo schizont maturation assays, which preclude determining the IC50s of delayed action antimalarials such as doxycycline. Using Plasmodium cynomolgi as a model for P. vivax , we determined the physiologically significant delayed death effect induced by doxycycline [IC 50(96 h) , 1,401 ± 607 nM]. As expected, IC 50(96 h) to chloroquine (20.4 nM), piperaquine (12.6 µM), and tafenoquine (1,424 nM) were not affected by extended exposure.
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2024
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2024
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2023
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2023
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2022
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2022
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2022
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2022
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2022
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2022
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2021
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2021
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2021
Year:
2021
Collaborators (13)
Sergio Romeo
Associate Professor
Università degli Studi di Torino
Donatella Taramelli
Full Professor of Pathology
University of Milan
SILVIA PARAPINI
Associate Professor in Biotechnology and Methods in Laboratory Medicine
University of Milan
Sarah Auburn
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Benoit Malleret
Assistant Professor
National University of Singapore (NUS)
Laurent Renia
Professor of Infectious Diseases
Lee Kong Chian School of Medicine, Nanyang Technological University
Daniel Pletzer
Associate Professor
University of Otago
Anna Sparatore
Full Professor
Università degli Studi di Torino
Osamu Kaneko
Dean
Institute of Tropical Medicine, Nagasaki University
Annelise E. Barron
Associate Professor
Stanford University
Gabriela Minigo
Charles Darwin University
Giulio Dondio
Contract Professor
University of Pavia
Wenn-Chyau Lee
Senior Lecturer
University of Malaya
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