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Recent Grants
Grant: Close
Vascular involvement in post-COVID-19 syndromes
Open Date: 2022-10-01
Close Date: 2025-09-01
Grant: Close
MICA: A Developmental Trial of Personalised Medicine for Repurposing Zibotentan, a Selective Endothelin A Receptor Blocker, in Microvascular Angina (PRIZE)
Open Date: 2019-06-01
Close Date: 2023-12-01
Articles (11)
Summary Microvascular arterial disease in the heart manifest as coronary microvascular dysfunction. This condition causes microvascular angina and is associated increased morbidity and mortality. Microvascular arterial disease in the brain is referred to as cerebrovascular small vessel disease. This is responsible for 45% of dementias and 25% of ischaemic strokes. The heart and brain share similar vascular anatomy and common pathogenic risk factors are associated with the development of both coronary microvascular dysfunction and cerebrovascular small vessel disease. Microvascular disease in the heart and brain also appear to share common multisystem pathophysiological mechanisms. Further studies on diagnostic approaches, epidemiology and development of disease-modifying therapy seem warranted.
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2023
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2023
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2022
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2022
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2022
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2022
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2022
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2022
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2022
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2022
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2022
Collaborators (36)
Hugh Welch
University of Bristol
Dirk Husmeier
University of Glasgow
Mevhibe Hocaoglu
King’s College London
Shaney Barratt
University of Bristol
Zsofia Dora Drobni
Semmelweis University
Abraham Olvera-Barrios
University College London
Rachael Hughes
University of Bristol
Alex Dregan
King’s College London
Angela Wood
Reader in Health Data Science
University of Cambridge
Julie Whitney
King's College Hospital
Padraig Kitterick
Head of Audiological Science
-
Catherine Bagot
University of Glasgow
Elena Raffetti
University of Cambridge
David Connell
Honorary, Honorary Senior Lecturer
University of Dundee
David Hughes
Lecturer in Health Data Science
University of Liverpool
Jonathan Evans
University of Bristol
Harmony Reynolds
Saul J. Farber Associate Professor of Medicine (Academic)
NYU School of Medicine
Alistair Church
-
Gareth Williams
King’s College London
Federico Biavati
Charité - Universitätsmedizin Berlin
Huan Wang
Principal Investigator (Tenure-track Lecturer)
University of Dundee
Deepti Gurdasani
Associate Professor of AI in Public Health
University of New South Wales
Sharmin Shabnam
University of Leicester
Umesh Kadam
Professor of General Practice and Public Health Research
University of Exeter
Richard Killick
King's College London
Andrew Morrow
University of Glasgow
Tim Dong
University of Bristol
Ify Mordi
Academic, Clinical Sen Lecturer/Honorary Cons (Teaching and Research)
University of Dundee
Gwenetta Curry
Reader in Race, Ethnicity and Health
University of Edinburgh
Nicholas Hart
Professor of Respiratory and Critical Care Medicine
Guy's and St Thomas' NHS Foundation Trust
James Martin
University of Birmingham
John Pearl
Lecturer
University of Leicester
Ignacio Diez Lopez
-
Clea du Toit
University of Glasgow
GERSHAN DAVIS
University of Central Lancashire
Vasa Curcin
King’s College London
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