Caitlin O'Connor

Research Assistant Professor

University of Michigan

United States

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Caitlin O'Connor is a Research Assistant Professor at the University of Michigan, USA. Her research focuses on the role of protein phosphatase 2A (PP2A) in cancer biology, examining germline mutations, multidrug resistance, and synthetic lethality in various carcinomas. Recent publications highlight her work on PP2A modulation and its implications for cancer treatment strategies.

Articles (8)

Year:

2025

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2023

Year:

2023

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2022

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2022

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2020

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2020

Year:

2020

Collaborators (1)

Analisa DiFeo

Associate Professor

University of Michigan–Ann Arbor

UNITED STATES

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Caitlin O'Connor

Research Interests

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Articles (8)

Germline mutations in PPP2R1B in patients with a personal and family history of cancer

PP2A modulation overcomes multidrug resistance in chronic lymphocytic leukemia via mPTP-dependent apoptosis

Small-Molecule–Mediated Stabilization of PP2A Modulates the Homologous Recombination Pathway and Potentiates DNA Damage-Induced Cell Death

Biased holoenzyme assembly of protein phosphatase 2A (PP2A): From cancer to small molecules

Targeting Ribonucleotide Reductase Induces Synthetic Lethality in PP2A-Deficient Uterine Serous Carcinoma

Inactivation of PP2A by a recurrent mutation drives resistance to MEK inhibitors

The SRG rat, a Sprague-Dawley Rag2/Il2rg double-knockout validated for human tumor oncology studies

Splice of Life for Cancer: Missplicing of PPP2R5A by Mutant SF3B1 Leads to MYC Stabilization and Tumorigenesis

Collaborators (1)

Analisa DiFeo

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