Caitlyn Holmes

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Faculty, Assistant Professor

University of Minnesota

United States

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About

Dr. Caitlyn Holmes is an Assistant Professor at the University of Minnesota in the United States. Her research focuses on the pathogenesis of Klebsiella pneumoniae, including its genomic evolution and mechanisms of virulence. Recent publications highlight her work on integrating genomic data to explore in vivo fitness mechanisms and the impact of arginine on bacterial phenotypes.

Recent Grants

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Defining macrophage defense during Klebsiella pneumoniae bacteremia

Open Date: 2024-05-06

Close Date: 2026-04-30

Articles (10)

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2025

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2025

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2025

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2025

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2025

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2024

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2024

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2024

Collaborators (2)

Matthew Waldor

Edward H. Kass Professor of Medicine

Brigham and Women's Hospital

UNITED STATES

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Daria Van Tyne

Assistant Professor

University of Pittsburgh

UNITED STATES

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Caitlyn Holmes

Research Interests

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Contact this professor

About

Recent Grants

Articles (10)

Arginine regulates the mucoid phenotype of hypervirulent Klebsiella pneumoniae

Integrating genomic and Tn-Seq data to identify common in vivo fitness mechanisms across multiple bacterial species

Klebsiella pneumoniae evolution in the gut leads to spontaneous capsule loss and decreased virulence potential

<i>Klebsiella pneumoniae</i> evolution in the gut leads to spontaneous capsule loss and decreased virulence potential

Bloodstream infections: mechanisms of pathogenesis and opportunities for intervention

Patterns of Klebsiella pneumoniae bacteremic dissemination from the lung

Patterns of <i>Klebsiella pneumoniae</i> bacteremic dissemination from the lung

Bloodstream infections: mechanisms of pathogenesis and opportunities for intervention

A novel method for integrating genomic and Tn-Seq data to identify common <italic>in vivo</italic> fitness mechanisms across multiple bacterial species

Arginine Regulates the Mucoid Phenotype of Hypervirulent Klebsiella pneumoniae

Collaborators (2)

Matthew Waldor

Daria Van Tyne

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