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Caleb Lareau

Has grant

Assistant Member

Memorial Sloan Kettering Cancer Center

United States

Research Interests

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Recent Grants

Grant: Open

Programmable nucleic acid cytometry for unraveling heterogeneity in tumors and therapies

Open Date: 2025-09-01

Close Date: 2028-08-31

Grant: Open

The Human DNA virome: from petabase scale to single-cell resolution

Open Date: 2024-09-20

Close Date: 2029-08-31

Grant: Close

Charting somatic evolution via single-cell multiomics

Open Date: 2023-09-01

Close Date: 2026-08-31

Grant: Close

Inference of variable chromatin loops in glioblastoma tumors and single-cells

Open Date: 2018-09-01

Close Date: 2020-08-31

Grant: Close

Graduate Research Fellow

Open Date: 2015-08-01

Close Date: 2018-08-01

Articles (20)

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Collaborators (16)

Yajie Yin

Stanford University

UNITED STATES

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Yael David

Associate Member

Memorial Sloan Kettering Cancer Center

UNITED STATES

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Gilles Salles

Lymphoma Service, Chief

Memorial Sloan Kettering Cancer Center

UNITED STATES

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Payam Anthony Gammage

Professor of Mitochondrial Biology

University of Glasgow

UNITED KINGDOM

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Livius Penter

Max-Eder Research Group leader

Charité - Universitätsmedizin Berlin

GERMANY

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Patrick Chinnery

Professor of Neurology

Newcastle University

UNITED KINGDOM

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Gunjan Shah

Memorial Sloan Kettering Cancer Center

UNITED STATES

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Pradeep Natarajan

Associate Professor

Harvard Medical School

UNITED STATES

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Ryan Dhindsa

Assistant Professor

Baylor College of Medicine

UNITED STATES

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Dana Pe'er

Sloan Kettering Institute

UNITED STATES

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Zhi Yu

Broad Institute

UNITED STATES

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Niels Asger Jakobsen

University of Oxford

UNITED KINGDOM

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Marion Subklewe

LMU University Hospital

GERMANY

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Christopher B. Jackson

University of Helsinki

FINLAND

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Giulio Cassanello

Faculty

Ospedale San Raffaele

ITALY

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Patrick Maschmeyer

Professor of AI-based Predictive Immune Analytics

University of Lübeck

GERMANY

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Caleb Lareau

Research Interests

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Recent Grants

Articles (20)

Crowdsourcing functional cell therapy binders from generative artificial intelligence

Clonal haematopoiesis subtypes confer dose-dependent risk of serious bacterial infection

Regulation of immune signal integration and memory by inflammation-induced chromosome conformation

Sequence and structural determinants of efficacious de novo chimaeric antigen receptors

Artefacts in single-cell mtDNA analyses misinform phylogenies

Non-Enzymatic MGO-Glycation of SRSF2 Drives RNA Mis-Splicing

Clonal tracing with somatic epimutations reveals dynamics of blood ageing

Cell type–specific purifying selection of synonymous mitochondrial DNA variation

Dynamics of Immune Reconstitution and Impact on Outcomes across CAR-T Cell Products in Large B-cell Lymphoma

Engineering T cells with a membrane-tethered version of SLP-76 overcomes antigen-low resistance to CAR T cell therapy

Methods for multiplexing single-cell multi-omics

A pathogenic subpopulation of human glioma associated macrophages linked to glioma progression

CAR-engineered lymphocyte persistence is governed by a FAS ligand-FAS autoregulatory circuit

Clonal lineage tracing of innate immune cells in human cancer

Engineering mtDNA deletions by reconstituting end joining in human mitochondria

Epigenomic State Transitions Characterize Tumor Progression in Mouse Lung Adenocarcinoma (vol 38, pg 212, 2020)

Functionally dominant hotspot mutations of mitochondrial ribosomal RNA genes in cancer

Independent mechanisms of inflammation and myeloid bias in VEXAS syndrome

Pioneering single-cell intracellular metagenomics: a window into microbe-immune interactions at barrier tissues

Population-scale sequencing resolves correlates and determinants of latent Epstein-Barr Virus infection

Collaborators (16)

Yajie Yin

Yael David

Gilles Salles

Payam Anthony Gammage

Livius Penter

Patrick Chinnery

Gunjan Shah

Pradeep Natarajan

Ryan Dhindsa

Dana Pe'er

Zhi Yu

Niels Asger Jakobsen

Marion Subklewe

Christopher B. Jackson

Giulio Cassanello

Patrick Maschmeyer

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