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Carla Cruz

Has grant

Associate Professor

Universidade da Beira Interior

Portugal

Research Interests

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Professors in Portugal Professors in Biochemistry Biochemistry professors in Portugal

Recent Grants

Grant: Open

AquaClean

Open Date: 2024-10-01

Close Date: 2027-09-01

Grant: Close

Novel approach to control let-7e miRNA biogenesis: Unveiling the relationship between structure and function of let-7e precursor miRNA/nucleolin complex

Open Date: 2022-11-01

Close Date: 2023-10-01

Grant: Close

miRNAs biomarkers for lung cancer detection

Open Date: 2022-06-01

Close Date: 2023-05-01

Grant: Close

Vaginal gel for topical application in precancerous lesions caused by the Human Papilloma Virus

Open Date: 2022-03-01

Close Date: 2024-02-01

Grant: Close

BInov 2021 Award, Innovation Grant funded by the Southern and Autonomous Regions Regional Section (SRSRA) of the Order of Pharmacists

Open Date: 2021-12-01

Close Date:

Articles (32)

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Collaborators (23)

Fani Sousa

Associate Professor with Habilitation

Universidade da Beira Interior

PORTUGAL

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Tiago Rosado

Guest Assistant Professor

Polytechnic Institute of Bragança

PORTUGAL

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António Paulo

PORTUGAL

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David Monchaud

CNRS

Université de Bourgogne

FRANCE

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Luís Passarinha

Professor and Researcher

Universidade da Beira Interior

PORTUGAL

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Ana Belchior

Professor Associado Convidado. Responsável pela UC de Efeitos Biológicos das Radiações

Universidade de Lisboa Instituto Superior Técnico

PORTUGAL

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Marília Figueira

PhD integrated member

Universidade da Beira Interior

PORTUGAL

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Jéssica Nunes

Invited Assistant Professor

Universidade da Beira Interior

PORTUGAL

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Claudio Nastruzzi

Docenti di ruolo di IIa fascia

University of Ferrara

ITALY

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Eurico Cabrita

Associate Professor

Faculdade de Ciências da Universidade de Lisboa

PORTUGAL

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Rui Medeiros

Instituto Português de Oncologia do Porto

PORTUGAL

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Cláudio Maia

Assistant Professor

Universidade da Beira Interior Faculdade de Ciências da Saúde

PORTUGAL

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Silvia Socorro

Vice-Rector for Research, Innovation and Development

Universidade da Beira Interior

PORTUGAL

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Izamara Gomes Maocha

Universidade da Beira Interior

PORTUGAL

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Eugenia Gallardo

Membro Integrado do RISE-HEALTH

Universidade da Beira Interior

PORTUGAL

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Cândida Tomaz

Associate Professor

Universidade da Beira Interior

PORTUGAL

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Roberto Quesada

Profesor Titular

Universidad de Burgos

SPAIN

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Eduardo Fernandez-Megia

Universidade de Santiago de Compostela

SPAIN

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Alberto Paradela

senior scientist

Centro Nacional de Biotecnología

SPAIN

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Yi Lu

Professor

University of Texas at Austin

UNITED STATES

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Alexandra Fernandes

Full Professor

Universidade de Aveiro

PORTUGAL

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Jean-Christophe Andrau

DR2

CNRS Délégation Languedoc-Roussillon

FRANCE

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Pedro Baptista

Universidade de Aveiro

PORTUGAL

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Carla Cruz

Research Interests

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Recent Grants

Articles (32)

Modulating PhpC bioavailability and cellular activity in lung cancer cells via gold nanoparticle functionalization

B-MYB (MYBL2): from cell cycle regulator to an oncogenic player

Aptamer-Functionalized Liposomes for Targeted Delivery of Anticancer Drugs in Lung Cancer

Harnessing microRNAs in lung cancer: The future of diagnosis and precision therapy

Synthesis of 1,10-Phenanthroline-2,9-bistriazoles: Evaluation as G-Quadruplex Binders and Anti-Tumor Activity

Exploring the G-Quadruplex Formation of AS1411 Derivatives

Sensitive fluorescent detection of SARS-CoV-2 RNA using an enzymatic-based method

Vaginal formulation development: A strategy based on aptamer-guided liposome for human papillomavirus-induced lesions

miRNA-155-3p and miRNA-3196 as Potential Biomarkers in Liquid Biopsies of Non-Small Cell Lung Cancer Patients

Cellular modulation of a G-quadruplex structure found in the lung cancer-related microRNA-3196

G-Quadruplex Conformational Switching for miR-155-3p Detection Using a Ligand-Based Fluorescence Approach

I-motif formation in the promoter region of the B-MYB proto-oncogene

Aptamers for the Delivery of Plant-Based Compounds: A Review

AT11-guided liposomes for oral cancer cells: From characterization towards in vitro evaluation

Enhanced targeted liposomal delivery of imiquimod via aptamer functionalization for head and neck cancer therapy

Nanotherapy for human papillomavirus-associated cancers: breakthroughs and challenges

Detecting mir-155-3p through a Molecular Beacon Bead-Based Assay

Evaluation of miR-155 silencing using a molecular beacon in human lung adenocarcinoma cell line

Imiquimod-Loaded Nanosystem for Treatment Human Papillomavirus-Induced Lesions

G-quadruplex forming motifs in the promoter region of the B-MYB proto-oncogene

Targeting of G‐quadruplex DNA with <sup>99m</sup>Tc(I)/Re(I) Tricarbonyl Complexes Carrying Pyridostatin Derivatives

Targeting proto-oncogene B-MYB G-quadruplex with a nucleic acid–based fluorescent probe

Assessment of Aptamer as a Potential Drug Targeted Delivery for Retinal Angiogenesis Inhibition

Proteomics profiling of vitreous humor reveals complement and coagulation components, adhesion factors, and neurodegeneration markers as discriminatory biomarkers of vitreoretinal eye diseases

Structural Perspective into the Interaction of an Oncogenesis‐Relevant pre‐miRNA G‐Quadruplex Ligand Carrier with the Protein Nucleolin

G-Quadruplex Aptamer-Ligand Characterization

Gallic Acid–Triethylene Glycol Aptadendrimers Synthesis, Biophysical Characterization and Cellular Evaluation

Synthesis and evaluation of 2,9-disubstituted-1,10-phenanthroline derivatives as G-quadruplex binders

Stabilization of a DNA aptamer by ligand binding

Nucleolin: a binding partner of G-quadruplex structures

Targeting a G-quadruplex from let-7e pre-miRNA with small molecules and nucleolin

Molecular Beacon for Detection miRNA-21 as a Biomarker of Lung Cancer

Collaborators (23)

Fani Sousa

Tiago Rosado

António Paulo

David Monchaud

Luís Passarinha

Ana Belchior

Marília Figueira

Jéssica Nunes

Claudio Nastruzzi

Eurico Cabrita

Rui Medeiros

Cláudio Maia

Silvia Socorro

Izamara Gomes Maocha

Eugenia Gallardo

Cândida Tomaz

Roberto Quesada

Eduardo Fernandez-Megia

Alberto Paradela

Yi Lu

Alexandra Fernandes

Jean-Christophe Andrau

Pedro Baptista

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