Carlos Martin

Microbiology Professor

Universidad de Zaragoza

Spain

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Carlos Martin is a Microbiology Professor at the University of Zaragoza, Spain. His research focuses on tuberculosis vaccination, specifically the efficacy of BCG and MTBVAC, and their roles in inducing immune responses against lung metastasis and asthma protection. Recent publications highlight his investigations into the immunological mechanisms of these vaccines and their effects on various animal models.

Carlos Martin

Research Interests

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Articles (19)

NK cells mediate preventive efficacy of intravenous BCG against lung metastasis in mice

Correlation between systemic allergen desensitisation and long-term asthma protection in mice following intravenous administration of the live tuberculosis vaccine MTBVAC

Low-dose <i>M.tb</i> infection but not BCG or MTBVAC vaccination enhances heterologous antibody titres in non-human primates

MTBVAC induces superior antibody titers and IgG avidity compared to BCG vaccination in non-human primates

Susceptibility testing of the live attenuated tuberculosis vaccine BCG and the vaccine candidate MTBVAC to currently WHO-recommended anti-tuberculosis drugs by the European committee on antimicrobial susceptibility testing (EUCAST) method

BCG-activation of leukocytes is sufficient for the generation of donor-independent innate anti-tumor NK and γδ T-cells that can be further expanded <i>in vitro</i>

Natural mutations in the sensor kinase of the PhoPR two-component regulatory system modulate virulence of ancestor-like tuberculosis bacilli

BCG-activation of leukocytes is sufficient for the generation of donor-independent innate anti-tumor NK and γδ T-cells that can be further expanded <i>in vitro</i>

Natural mutations in the sensor kinase of the PhoPR two-component regulatory system modulate virulence of ancestor-like tuberculosis bacilli

Intravenous administration of BCG in mice promotes natural killer and T cell-mediated antitumor immunity in the lung

MTBVAC: A Tuberculosis Vaccine Candidate Advancing Towards Clinical Efficacy Trials in TB Prevention

Galleria mellonella as an infection model for the virulent Mycobacterium tuberculosis H37Rv

Novel intravesical bacterial immunotherapy induces rejection of BCG-unresponsive established bladder tumors

The Lack of the TetR-Like Repressor Gene BCG_2177c (Rv2160A) May Help Mycobacteria Overcome Intracellular Redox Stress and Survive Longer Inside Macrophages When Surrounded by a Lipid Environment

The Mycobacterium tuberculosis PhoPR virulence system regulates expression of the universal second messenger c-di-AMP and impacts vaccine safety and efficacy

MTBVAC, a live TB vaccine poised to initiate efficacy trials 100 years after BCG

TIPICO XI: report of the first series and podcast on infectious diseases and vaccines (aTIPICO)

Pulmonary MTBVAC vaccination induces immune signatures previously correlated with prevention of tuberculosis infection.

Pulmonary MTBVAC vaccination induces immune signatures previously correlated with prevention of tuberculosis infection

Collaborators (3)

Sharon Kendall

Roland Brosch

Jesús Gonzalo-Asensio

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