Carly Baehr

Assistant Professor

University of Minnesota

United States

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Carly Baehr is an Assistant Professor at the University of Minnesota, United States. Her research focuses on the development of monoclonal antibodies targeting opioid mixtures, specifically fentanyl and carfentanil, to mitigate their effects in both animal models and human applications. Recent publications include work on the biophysical profiling of these antibodies and their potential efficacy in addressing opioid toxicity and addiction.

Articles (19)

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2025

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2020

Collaborators (4)

Spencer Erickson

University of Minnesota

UNITED STATES

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Beth Thielen

University of Minnesota

UNITED STATES

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Marco Pravetoni

University of Minnesota Medical School

UNITED STATES

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Maxim Cheeran

University of Minnesota

UNITED STATES

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Carly Baehr

Research Interests

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Articles (19)

A humanized monoclonal antibody attenuates carfentanil self-administration in nonhuman primates

In vitro biophysical and pharmacological profiling predicts in vivo efficacy of anti-carfentanil monoclonal antibodies in mice

Bivalent Hapten Display Strategies for Conjugate Vaccines Targeting Opioid Mixtures Containing Fentanyl

A humanized monoclonal antibody attenuates fentanyl self-administration and reverses and prevents fentanyl-induced ventilatory depression in rhesus monkeys.

Monoclonal Antibodies Engineered with Fc Region Mutations to Extend Protection against Fentanyl Toxicity

Identification and biophysical characterization of a novel domain-swapped camelid antibody specific for fentanyl

The fentanyl-specific antibody FenAb024 can shield against carfentanil effects.

NK Cell and Monocyte Dysfunction in Multisystem Inflammatory Syndrome in Children

Structure-Based Engineering of Monoclonal Antibodies for Improved Binding to Counteract the Effects of Fentanyl and Carfentanil

IL-4 Predicts the Efficacy of a Candidate Antioxycodone Vaccine and Alters Vaccine-Specific Antibody-Secreting Cell Proliferation in Mice

Anti-Strychnine Immunoconjugate Reduces the Effects of Strychnine-Induced Toxicity in Mice

A trypanosome-derived immunotherapeutics platform elicits potent high-affinity antibodies, negating the effects of the synthetic opioid fentanyl

Structures of drug-specific monoclonal antibodies bound to opioids and nicotine reveal a common mode of binding

Advancing humanized monoclonal antibody for counteracting fentanyl toxicity towards clinical development

Preclinical Efficacy and Selectivity of Vaccines Targeting Fentanyl, Alfentanil, Sufentanil, and Acetylfentanyl in Rats

Pharmacological profiling of anti-fentanyl monoclonal antibodies in combination with naloxone in pre- and post-exposure models of fentanyl toxicity

A Membrane-Modulated Centrifugal Microdevice for Enzyme-Linked Immunosorbent Assay-Based Detection of Illicit and Misused Drugs.

Contribution of Antibody-Mediated Effector Functions to the Mechanism of Efficacy of Vaccines for Opioid Use Disorders

Monoclonal Antibodies Counteract Opioid-Induced Behavioral and Toxic Effects in Mice and Rats

Collaborators (4)

Spencer Erickson

Beth Thielen

Marco Pravetoni

Maxim Cheeran

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