Carmen Blanco-Aparicio

Head of Biology Section

Centro Nacional de Investigaciones Oncológicas

Spain

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Carmen Blanco-Aparicio is the Head of the Biology Section at the Centro Nacional de Investigaciones Oncológicas in Spain. Her research interests focus on the mechanisms underlying tumor growth and metastasis, with recent publications addressing novel biomarker discovery and therapeutic strategies. She has explored the effects of drug-screening platforms on brain metastasis and investigated synthetic lethality in BRCA1-deficient cells, contributing significantly to the fields of oncology and pharmacology.

Articles (10)

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2023

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2022

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2022

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2022

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2022

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2021

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2021

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2021

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2020

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2020

Collaborators (5)

Daniel Fisher

FRANCE

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Sandra Rodriguez-Perales

Head of Molecular Cytogenetics & Genome Editing Unit

Centro Nacional de Investigaciones Oncológicas

SPAIN

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SONIA MARTINEZ GONZALEZ

Head of Medicinal Chemistry

Centro Nacional de Investigaciones Oncológicas

SPAIN

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Lucia Jimenez

Profesora de Bioquímica

Universidad Camilo José Cela

SPAIN

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Kathy Gately

Clinical Senior Lecturer

Trinity College Dublin

IRELAND

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Carmen Blanco-Aparicio

Research Interests

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Articles (10)

Endoglin, a Novel Biomarker and Therapeutical Target to Prevent Malignant Peripheral Nerve Sheath Tumor Growth and Metastasis

A clinically compatible drug-screening platform based on organotypic cultures identifies vulnerabilities to prevent and treat brain metastasis

OGG1 Inhibition Triggers Synthetic Lethality and Enhances The Effect of PARP Inhibitor Olaparib in BRCA1-Deficient TNBC Cells

Screening Health-Promoting Compounds for Their Capacity to Induce the Activity of FOXO3

mTORC2 Is the Major Second Layer Kinase Negatively Regulating FOXO3 Activity

Co-Targeting PIM Kinase and PI3K/mTOR in NSCLC

Omipalisib inspired macrocycles as dual PI3K/mTOR inhibitors

Macrocyclization as a Source of Desired Polypharmacology. Discovery of Triple PI3K/mTOR/PIM Inhibitors

Global hyperactivation of enhancers stabilizes human and mouse naive pluripotency through inhibition of CDK8/19 Mediator kinases.

Induction of Lysosome Membrane Permeabilization as a Therapeutic Strategy to Target Pancreatic Cancer Stem Cells

Collaborators (5)

Daniel Fisher

Sandra Rodriguez-Perales

SONIA MARTINEZ GONZALEZ

Lucia Jimenez

Kathy Gately

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