Carol J Thiele

Deputy Chief

Institute of Cancer Research

United States

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Carol J Thiele is the Deputy Chief at the Center for Cancer Research in the United States. Her research focuses on neuroblastoma, particularly the roles of MYCN and associated regulatory mechanisms in oncogenesis. Recent articles highlight her work on tumor suppressor genes and innovative therapies, including the use of chimeric antigen receptor T cells against neuroblastoma.

Articles (5)

Year:

2025

Year:

2023

Year:

2022

Year:

2022

Year:

2021

Collaborators (1)

Jack Shern

Head, Tumor Evolution and Genomics Section

National Institutes of Health

UNITED STATES

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Carol J Thiele

Research Interests

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Articles (5)

Cohesin Loading Factor NIPBL Is Essential for MYCN Expression and MYCN-Driven Oncogenic Transcription in Neuroblastoma

HAND2 Assists MYCN Enhancer Invasion to Regulate a Noradrenergic Neuroblastoma Phenotype

Loss of CASZ1 tumor suppressor linked to oncogenic subversion of neuroblastoma core regulatory circuitry

Anti-GD2 Antibodies Conjugated to IL15 and IL21 Mediate Potent Antitumor Cytotoxicity against Neuroblastoma

Preclinical testing of chimeric antigen receptor T cells in neuroblastoma mouse models

Collaborators (1)

Jack Shern

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