Carolyn Brown

Professor

The University of British Columbia

Canada

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Professor Carolyn Brown is a faculty member at the University of British Columbia in Canada. Her research primarily focuses on X-chromosome inactivation, including the origin and function of the XIST RNA and its role in gene silencing. Recent publications explore the genetic and epigenetic factors influencing escape from X-chromosome inactivation and the interaction domains involved in chromatin remodeling.

Articles (10)

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2025

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2025

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2023

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2023

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2023

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2022

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2021

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2021

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2021

Year:

2020

Collaborators (1)

Wyeth Wasserman

Professor

The University of British Columbia

CANADA

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Carolyn Brown

Research Interests

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Articles (10)

Human XIST: Origin and Divergence of a <i>cis</i>-Acting Silencing RNA

Recruitment of chromatin remodelers by XIST B-repeat region is variably dependent on HNRNPK

Derivation of a minimal functional XIST by combining human and mouse interaction domains

Refining the genomic determinants underlying escape from X-chromosome inactivation

Out of the Silence: Insights into How Genes Escape X-Chromosome Inactivation

Multiple distinct domains of human XIST are required to coordinate gene silencing and subsequent heterochromatin formation

Contribution of genetic and epigenetic changes to escape from X-chromosome inactivation

Cross-species examination of X-chromosome inactivation highlights domains of escape from silencing

Independent domains for recruitment of PRC1 and PRC2 by human XIST

Genes that escape from X‐chromosome inactivation: Potential contributors to Klinefelter syndrome

Collaborators (1)

Wyeth Wasserman

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