Carolyn Nicole Brown

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Professional Research Assistant/Lab Manager

University of Colorado Boulder

United States

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Molecular computation by the CaMKII holoenzyme

Open Date: 2022-08-01

Close Date: 2025-08-01

Articles (8)

Year:

2023

Year:

2023

Year:

2022

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2021

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2020

Year:

2020

Year:

2020

Year:

2020

Collaborators (2)

Katharina Hopp

Assistant Professor

University of Colorado Anschutz Medical Campus

UNITED STATES

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K. Ulrich Bayer

Tenured Full Professor

University of Colorado Anschutz Medical Campus

UNITED STATES

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Carolyn Nicole Brown

Research Interests

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Recent Grants

Articles (8)

LTP induction by structural rather than enzymatic functions of CaMKII

Short-term CaMKII inhibition with tatCN19o does not erase pre-formed memory in mice and is neuroprotective in pigs.

Aβ-induced synaptic impairments require CaMKII activity that is stimulated by indirect signaling events

Surgical procedures suppress autophagic flux in the kidney.

The CaMKII K42M and K42R mutations are equivalent in suppressing kinase activity and targeting

The effect of trehalose on autophagy-related proteins and cyst growth in a hypomorphic Pkd1 mouse model of autosomal dominant polycystic kidney disease.

Increased mTOR and suppressed autophagic flux in the heart of a hypomorphic Pkd1 mouse model of autosomal dominant polycystic kidney disease.

The effect of MEK1/2 inhibitors on cisplatin-induced acute kidney injury (AKI) and cancer growth in mice.

Collaborators (2)

Katharina Hopp

K. Ulrich Bayer

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