Carsten Culmsee

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Profesor for Clinical Pharmacy

Philipps-Universität Marburg

Germany

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About

Carsten Culmsee is a Professor for Clinical Pharmacy at Philipp University of Marburg, Germany. His research focuses on the structural characterization and bioactivity profiling of fungal peptaibiotics, mitochondrial dysfunction, ferroptosis, and the impacts of natural products on cellular resilience against age-related pathologies. Recent publications highlight his work on mitochondrial integrity, inflammation, and the pharmacological implications of self-medication in clinical settings.

Recent Grants

Grant: Close

Role of HIF-PHD in mitochondrial pathways of cell death after cerebral ischemia

Open Date: 2018-01-01

Close Date: 2021-01-01

Grant: Close

Effects of Cimicifuga extract Ze 450 on mitochondrial resilience in neuronal cells

Open Date: 2016-01-01

Close Date: 2019-01-01

Grant: Close

Funktionelle Expression von Connexin-43 in Mitochondrien

Open Date: 2015-01-01

Close Date: 2018-01-01

Grant: Close

Neurobiology of affective disorders: a translational perspective on brain structure and function

Open Date: 2014-01-01

Close Date: 2021-01-01

Grant: Close

EpimiRNA: MicroRNAs in the pathogenesis, treatment and prevention of epilepsy

Open Date: 2013-01-01

Close Date: 2018-01-01

Articles (17)

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2024

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2022

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2022

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2022

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2021

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2021

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2021

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2020

Collaborators (13)

Klas Blomgren

Karolinska Institutet

SWEDEN

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Eva Böttcher-Friebertshäuser

Philipps-Universität Marburg

GERMANY

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Christiane Herden

Justus Liebig University

GERMANY

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Behrooz H. Yousefi

Philipps-Universität Marburg

GERMANY

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Christoph Hartwig

GERMANY

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Marco Rust

Professor (W2)

Philipps-Universität Marburg

GERMANY

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Prof. Joerg Walter Bartsch

Professor/Lab Head

Philipps-Universität Marburg Fachbereich Medizin

GERMANY

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Christoph Rummel

Justus Liebig University

GERMANY

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Nikolaus Plesnila

LMU University Hospital

GERMANY

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Markus Oberpaul

GERMANY

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Amalia Dolga

Associate Professor

University of Groningen

NETHERLANDS

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Andreas Vilcinskas

Justus Liebig University

GERMANY

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Magdalena Gąssowska-Dobrowolska

Polska Akademia Nauk Instytut Medycyny Doswiadczalnej i Klinicznej im M Mossakowskiego

POLAND

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Carsten Culmsee

Research Interests

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Recent Grants

Articles (17)

Structural characterization and bioactivity profiling of the fungal peptaibiotic tolypin reveal protective effects against influenza viruses

Drp1 depletion protects against ferroptotic cell death by preserving mitochondrial integrity and redox homeostasis

Novel Insights into Parkin–Mediated Mitochondrial Dysfunction and “Mito-Inflammation” in α-Synuclein Toxicity. The Role of the cGAS–STING Signalling Pathway

AMPK Activation by Cimicifuga racemosa Extract Ze 450 Is Associated with Metabolic Effects and Cellular Resilience against Age-Related Pathologies in Different Tissue Cell Types

Correction: Dying transplanted neural stem cells mediate survival bystander effects in the injured brain

Mitochondrial Reactive Oxygen Species Formation Determines ACSL4/LPCAT2-Mediated Ferroptosis

n-3 Polyunsaturated Fatty Acids Modulate LPS-Induced ARDS and the Lung–Brain Axis of Communication in Wild-Type versus Fat-1 Mice Genetically Modified for Leukotriene B4 Receptor 1 or Chemerin Receptor 23 Knockout

Flavonoid–Phenolic Acid Hybrids Are Potent Inhibitors of Ferroptosis via Attenuation of Mitochondrial Impairment

Radiotracers for Imaging of Inflammatory Biomarkers TSPO and COX-2 in the Brain and in the Periphery

Clinical relevance of potential self-medication drug interactions in antineoplastic and immune-modulating therapy among online pharmacy customers

Treat more than heat—New therapeutic implications of Cimicifuga racemosa through AMPK-dependent metabolic effects

Cytochrome c Oxidase Inhibition by ATP Decreases Mitochondrial ROS Production

SK-Channel Activation Alters Peripheral Metabolic Pathways in Mice, but Not Lipopolysaccharide-Induced Fever or Inflammation

Inhibition of Carbonic Anhydrase 2 Overcomes Temozolomide Resistance in Glioblastoma Cells

Cofilin1 oxidation links oxidative distress to mitochondrial demise and neuronal cell death

Cimicifuga racemosa Extract Ze 450 Re-Balances Energy Metabolism and Promotes Longevity

The neuroprotective role of microglial cells against amyloid beta‐mediated toxicity in organotypic hippocampal slice cultures

Collaborators (13)

Klas Blomgren

Eva Böttcher-Friebertshäuser

Christiane Herden

Behrooz H. Yousefi

Christoph Hartwig

Marco Rust

Prof. Joerg Walter Bartsch

Christoph Rummel

Nikolaus Plesnila

Markus Oberpaul

Amalia Dolga

Andreas Vilcinskas

Magdalena Gąssowska-Dobrowolska

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