Cassandra Holbert

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Assistant Professor

Loyola University Maryland

United States

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About

Dr. Cassandra Holbert is an Assistant Professor at Loyola University Maryland in the United States. Her research focuses on the role of polyamines in cancer biology, exploring their influence on tumor microenvironments and immune responses. Recent publications highlight her investigations into polyamine metabolism, therapeutic applications, and the intersection with cancer treatment strategies.

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The role of the tumor immune microenvironment in the effectiveness of polyamine analogue, ivospemin, against ovarian cancer

Open Date: 2023-12-01

Close Date: 2024-12-01

Articles (10)

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2024

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2023

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2022

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2022

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2022

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2022

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2022

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University of Florida College of Medicine

UNITED STATES

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Cassandra Holbert

Research Interests

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About

Recent Grants

Articles (10)

Polyamines: the pivotal amines in influencing the tumor microenvironment

Difluoromethylornithine rebalances aberrant polyamine ratios in Snyder–Robinson syndrome

Polyamine-Based Nanostructures Share Polyamine Transport Mechanisms with Native Polyamines and Their Analogues: Significance for Polyamine-Targeted Therapy

Self-Assembled Alkylated Polyamine Analogs as Supramolecular Anticancer Agents

Histone deacetylase 10 liberates spermidine to support polyamine homeostasis and tumor cell growth.

Helping the helpers: polyamines help maintain helper T-cell lineage fidelity.

Expanded Potential of the Polyamine Analogue SBP-101 (Diethyl Dihydroxyhomospermine) as a Modulator of Polyamine Metabolism and Cancer Therapeutic

Polyamines in cancer: integrating organismal metabolism and antitumour immunity.

Hyaluronate-coated perfluoroalkyl polyamine prodrugs as bioactive siRNA delivery systems for the treatment of peritoneal cancers

Autophagy induction by exogenous polyamines is an artifact of bovine serum amine oxidase activity in culture serum.

Collaborators (5)

David Oupicky

Tracy Murray Stewart

Chinmay M. Jogdeo

Xianzun Tao

Otto Phanstiel

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