Catherine Freudenreich

Professor

Tufts University

United States

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Articles (10)

Year:

2023

Year:

2022

Year:

2021

Year:

2021

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2021

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2020

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2020

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2020

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2020

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2020

Collaborators (6)

James Haber

Abraham and Etta Goodman Professor of Biology and Director, Rosenstiel Basic Medical Sciences Research Center

Brandeis University

UNITED STATES

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Benoit Palancade

FRANCE

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Karol Kramarz

Assistant professor

Uniwersytet Łódzki

POLAND

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Sergei Mirkin

Endowed Chair Professor

Tufts University

UNITED STATES

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Edmond Chan

Columbia University Irving Medical Center

UNITED STATES

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Lata Balakrishnan

Associate Professor

Indiana State University

UNITED STATES

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Catherine Freudenreich

Research Interests

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Articles (10)

Structure-forming CAG/CTG repeats interfere with gap repair to cause repeat expansions and chromosome breaks

The RNA export and RNA decay complexes THO and TRAMP prevent transcription-replication conflicts, DNA breaks, and CAG repeat contractions

Rad9-mediated checkpoint activation is responsible for elevated expansions of GAA repeats in CST-deficient yeast

Restarted replication forks are error-prone and cause CAG repeat expansions and contractions

Homologous recombination within repetitive DNA.

The nuclear pore primes recombination-dependent DNA synthesis at arrested forks by promoting SUMO removal

Structure-forming repeats and their impact on genome stability.

R-loops promote trinucleotide repeat deletion through DNA base excision repair enzymatic activities

A Timeless Tale: G4 structure recognition by the fork protection complex triggers unwinding by DDX 11 helicase

Repeat expansions confer WRN dependence in microsatellite-unstable cancers.

Collaborators (6)

James Haber

Benoit Palancade

Karol Kramarz

Sergei Mirkin

Edmond Chan

Lata Balakrishnan

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