Catherine Makarewich

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Assistant Professor

Cincinnati Children's Hospital Medical Center

United States

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About

Dr. Catherine Makarewich is an Assistant Professor at Cincinnati Children's Hospital Medical Center, USA. Her research focuses on the roles of microproteins and the DWORF gene in cardiovascular health, mitochondrial function, and metabolic regulation. Recent publications include studies on gene therapy for Duchenne muscular dystrophy and the impact of microproteins in cellular homeostasis and energy production.

Recent Grants

Grant: Open

Microprotein Regulation of Mitochondrial Function

Open Date: 2021-12-01

Close Date: 2026-11-30

Grant: Close

Dissecting the role of novel calcium regulatory proteins in the cardiovascular system

Open Date: 2018-05-01

Close Date: 2019-10-23

Grant: Close

Dissecting the role of novel calcium regulatory proteins in the cardiovascular system

Open Date: 2018-05-01

Close Date: 2022-12-31

Grant: Close

Elucidation of the Role of a Novel Cardiac Micropeptide in the Control of Heart Function and Dysfunction

Open Date: 2016-02-01

Close Date: 2018-04-30

Grant: Close

A Novel Approach to Inhibiting Hypertrophic Calcium Signaling without Reducing Contractility of Cardiac Myocytes

Open Date: 2011-07-01

Close Date: 2013-06-30

Articles (15)

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2025

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2022

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2022

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2020

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2020

Collaborators (1)

Gang Yao

Professor

University of Missouri Columbia

UNITED STATES

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Catherine Makarewich

Research Interests

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About

Recent Grants

Articles (15)

DWORF Gene Therapy Improves Cardiac Calcium Handling and Mitochondrial Function.

DWORF expression is reduced in a large animal model of Duchenne muscular dystrophy.

Microproteins in Metabolism

Emerging roles for microproteins as critical regulators of endoplasmic reticulum function and cellular homeostasis

Nanopore Detection of METTL3-Dependent m6A-Modified mRNA Reveals a New Mechanism Regulating Cardiomyocyte Mitochondrial Metabolism

CHKB-DT: A Long Noncoding RNA Critical for Cardiovascular Health

Microproteins: Overlooked regulators of physiology and disease

Dwarf Open Reading Frame (DWORF) Gene Therapy Ameliorated Duchenne Muscular Dystrophy Cardiomyopathy in Aged mdx Mice

DWORF Extends Life Span in a PLN-R14del Cardiomyopathy Mouse Model by Reducing Abnormal Sarcoplasmic Reticulum Clusters

Mitochondrial microproteins: critical regulators of protein import, energy production, stress response pathways, and programmed cell death

Exercise-Induced Long Noncoding RNAs As New Players in Cardiac Hypertrophy

An Integrated Approach for Microprotein Identification and Sequence Analysis

The cardiac-enriched microprotein mitolamban regulates mitochondrial respiratory complex assembly and function in mice

Gene Therapy with the DWORF Micropeptide Attenuates Cardiomyopathy in Mice

The hidden world of membrane microproteins

Collaborators (1)

Gang Yao

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