Chad Vezina

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University of Wisconsin-Madison

United States

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About

Chad Vezina is a Professor at the University of Wisconsin–Madison, USA. His research areas include urinary tract infections, steroid hormone imbalances, and tissue homeostasis, as evidenced by his recent publications. His work explores the roles of 5-HT in urethral defense mechanisms and the impact of selective serotonin reuptake inhibitors in various contexts, including pregnancy. Additionally, he investigates the cellular and molecular dynamics involved in prostatic fibrosis and orofacial clefts.

Recent Grants

Grant: Close

Prostate inflammation increases collagen and voiding dysfunction

Open Date: 2019-09-01

Close Date: 2023-06-01

Grant: Close

Regulation of Bladder Structure and Function by Micro-RNA29

Open Date: 2019-08-05

Close Date: 2023-04-30

Grant: Close

Influence of SSRI Use During Pregnancy and Lactation on Maternal Bone Health

Open Date: 2018-07-20

Close Date: 2023-04-30

Grant: Close

TCDD Reprograms Prostate Stroma and Causes Fibrosis to Induce Urinary Dysfunction

Open Date: 2018-05-01

Close Date: 2020-04-30

Grant: Close

Characterization of Emca4, the Rat Ortholog of the 8q24 Breast Cancer Risk Locus

Open Date: 2017-03-01

Close Date: 2022-02-28

Articles (18)

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2025

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2023

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2021

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2021

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2020

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2020

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2020

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2020

Collaborators (11)

Petra Popovics

Assistant Professor

Eastern Virginia Medical School

UNITED STATES

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Dale E. Bjorling

UNITED STATES

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Douglas Strand

Associate Professor

University of Texas Southwestern Medical Center

UNITED STATES

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Teresa Liu

Assistant Professor

St. John Fisher College

UNITED STATES

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William Ricke

Director

UNITED STATES

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Robert Lipinski

Associate Professor

University of Wisconsin-Madison

UNITED STATES

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Michael F Romero

Professor / Consultant

Mayo Clinic College of Medicine and Science

UNITED STATES

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Samantha Weaver

Assistant Professor

University of Wisconsin-Madison

UNITED STATES

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Wisam Awadallah

Case Western Reserve University School of Medicine

UNITED STATES

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Laura Hernandez

Professor

University of Wisconsin-Madison

UNITED STATES

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Robert Matusik

Professor

Vanderbilt University Medical Center

UNITED STATES

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Chad Vezina

Research Interests

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About

Recent Grants

Articles (18)

A 5-HT-mediated urethral defense against urinary tract infections

Effects of Selective Serotonin Reuptake Inhibitors and Ondansetron on Urinary Tract Infections in Pregnancy

Disruption of DNA methylation-mediated cranial neural crest proliferation and differentiation causes orofacial clefts in mice.

CCR2<sup>+</sup> monocytes/macrophages drive steroid hormone imbalance-related prostatic fibrosis

Roles of airway and intestinal epithelia in responding to pathogens and maintaining tissue homeostasis

Lack of expression of miR-29a/b1 impairs bladder function in male mice

Steroid hormone imbalance drives macrophage infiltration and Spp1/osteopontin<sup>+</sup> foam cell differentiation in the prostate

Peripartal treatment with low‐dose sertraline accelerates mammary gland involution and has minimal effects on maternal and offspring bone

Expression patterns of chemokine (C–C motif) ligand 2, prostaglandin F2A receptor and immediate early genes at mRNA level in the bovine corpus luteum after intrauterine treatment with a low dose of prostaglandin F2A

Impact of Fluoxetine Treatment and Folic Acid Supplementation on the Mammary Gland Transcriptome During Peak Lactation

Male Lower Urinary Tract Dysfunction: An Underrepresented Endpoint in Toxicology Research

Osteopontin Deficiency Ameliorates Prostatic Fibrosis and Inflammation

A NEW approach for characterizing mouse urinary pathophysiologies

A multi-omic investigation of male lower urinary tract symptoms: Potential role for JC virus

Prostatic osteopontin expression is associated with symptomatic benign prostatic hyperplasia.

GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation

Cyp1b1 directs Srebp-mediated cholesterol and retinoid synthesis in perinatal liver; Association with retinoic acid activity during fetal development

Radiation cystitis modeling: A comparative study of bladder fibrosis radio‐sensitivity in C57BL/6, C3H, and BALB/c mice

Collaborators (11)

Petra Popovics

Dale E. Bjorling

Douglas Strand

Teresa Liu

William Ricke

Robert Lipinski

Michael F Romero

Samantha Weaver

Wisam Awadallah

Laura Hernandez

Robert Matusik

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