Charis Eng

Professor and Vice Chair

Case Western Reserve University School of Medicine

United States

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About

Charis Eng is a Professor and Vice Chair at Case Western Reserve University School of Medicine in the United States. Her research focuses on the intersection of genomic studies and tumor biology, particularly in relation to PTEN variants and their implications in neurodevelopmental and neoplastic conditions. Recent articles include investigations into microbial interactions in tumor environments, the genomic landscape of thyroid tumors, and the impact of germline mutations on cancer risk and developmental outcomes.

Articles (21)

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2022

Collaborators (2)

Andrea Eisen

McMaster University

CANADA

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Olufunmilayo I. Olopade

University of Chicago

UNITED STATES

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Charis Eng

Research Interests

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About

Articles (21)

The new microbiome on the block: challenges and opportunities of using human tumor sequencing data to study microbes

Genomic diversity in functionally relevant genes modifies neurodevelopmental versus neoplastic risks in individuals with germline PTEN variants

Germline PTEN genotype-dependent phenotypic divergence during the early neural developmental process of forebrain organoids

Cell-free DNA fragmentomics and second malignant neoplasm risk in patients with PTEN hamartoma tumor syndrome

A Bi-Institutional Study of Gastrointestinal and Hepatic Manifestations in Children With PTEN Hamartoma Tumor Syndrome

Protocol for analyzing plasma cell-free DNA fragment end motifs from ultra-low-pass whole-genome sequencing

The Genomic Landscape of Benign and Malignant Thyroid Tumors from Individuals Carrying Germline PTEN Variants Is Distinct from Sporadic Thyroid Cancers

Genotype/phenotype correlations in multiple endocrine neoplasia type 2

Targeting NANOG and FAK via Cx26-derived cell-penetrating peptides in triple-negative breast cancer

Integrating somatic CNV and gene expression in breast cancers from women with PTEN hamartoma tumor syndrome

The mitochondrial genome as a modifier of autism versus cancer phenotypes in PTEN hamartoma tumor syndrome

Microbiomic profiles of bile in patients with benign and malignant pancreaticobiliary disease

Clinical Spectrum and Science Behind the Hamartomatous Polyposis Syndromes

Two’s Company, Three’s a Crowd: Rb1/Trp53/Pten Trifecta and Lung Cancer Molecular and Histopathologic Heterogeneity

Comparative Protein Structural Network Analysis Reveals C-Terminal Tail Phosphorylation Structural Communication Fingerprint in PTEN-Associated Mutations in Autism and Cancer

Cancer Risk Associated With PTEN Pathogenic Variants Identified Using Multigene Hereditary Cancer Panel Testing

Differential cell cycle checkpoint evasion by PTEN germline mutations associated with dichotomous phenotypes of cancer versus autism spectrum disorder

Physical Activity During Adolescence and Early-adulthood and Ovarian Cancer Among Women with a BRCA1 or BRCA2 Mutation

Molecular subtypes of epilepsy associated with post-surgical seizure recurrence

Brain single cell transcriptomic profiles in episodic memory phenotypes associated with temporal lobe epilepsy

Molecular and subregion mechanisms of episodic memory phenotypes in temporal lobe epilepsy

Collaborators (2)

Andrea Eisen

Olufunmilayo I. Olopade

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