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Charles OBrien

Professor of Medicine

University of Arkansas for Medical Sciences

United States

Research Interests

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Professors in United States Professors in Tissue Engineering Tissue Engineering professors in United States

Articles (15)

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2025

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2023

Collaborators (9)

Diana I Escalona-Vargas

Associate Professor

University of Arkansas for Medical Sciences

UNITED STATES

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Marta Diaz-delCastillo

VIP, Assistant Professor

Aarhus University

DENMARK

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Intawat Nookaew

UNITED STATES

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Li Juel Mortensen

Rigshospitalet

DENMARK

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Ryan Porter

Associate Professor (Tenured)

University of Arkansas for Medical Sciences

UNITED STATES

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Christina M Andreasen

Postodc

Odense University Hospital

DENMARK

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HA-NEUI KIM

University of Arkansas for Medical Sciences

UNITED STATES

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Jeffrey B. Stambough

Associate Professor

University of Arkansas for Medical Sciences

UNITED STATES

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Martin Blomberg Jensen

Clinical Professor

Københavns Universitet

DENMARK

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Charles OBrien

Research Interests

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Articles (15)

Deletion of the scavenger receptor Scarb1 in osteoblast progenitors and myeloid cells does not affect bone mass

Mechanisms of mitochondrial reactive oxygen species action in bone mesenchymal cells

Potent suppression of bone remodeling by denosumab does not blunt the anabolic response to romosozumab in mice

The Aging Landscape by scRNAseq of Mesenchymal Lineage Cells in Mouse Bone

Single-cell Transcriptomic Analysis Identifies Senescent Osteocytes that Trigger Bone Destruction in Breast Cancer Metastasis

Denosumab stimulates spermatogenesis in infertile men with preserved Sertoli cell capacity.

A new Col1a1 conditional knock-in mouse model to study osteogenesis imperfecta

RANKL-mediated osteoclast formation is required for bone loss in a murine model of <i>Staphylococcus aureus osteomyelitis</i>

Refining the identity of mesenchymal cell types associated with murine periosteal and endosteal bone

The NAD salvage pathway in mesenchymal cells is indispensable for skeletal development in mice

Reduced OPG expression by osteocytes may contribute to rebound resorption after denosumab discontinuation

CRISPR interference provides increased cell type-specificity compared to the Cre-loxP system

Deletion of the scavenger receptor Scarb1 in myeloid cells does not affect bone mass (Retraction of Vol 170, art no 116702, 2023)

Deletion of the scavenger receptor Scarb1 in osteoblast progenitors does not affect bone mass (vol 17, e0265893, 2022) (Retraction of Vol 17, art no E0265893, 2022)

Osteoclasts, Master Sculptors of Bone

Collaborators (9)

Diana I Escalona-Vargas

Marta Diaz-delCastillo

Intawat Nookaew

Li Juel Mortensen

Ryan Porter

Christina M Andreasen

HA-NEUI KIM

Jeffrey B. Stambough

Martin Blomberg Jensen

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