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Charles Rudin

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Memorial Sloan Kettering Cancer Center

United States

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Recent Grants

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Coordinating center for the NCI small cell lung cancer research consortium

Open Date: 2017-02-20

Close Date: 2022-01-31

Grant: Close

Immuno-PET imaging of high-grade neuroendocrine lung tumors using 89Zr-rovalpituzumab, a DLL3-targeting monoclonal antibody

Open Date: 2017-01-01

Close Date: 2021-12-31

Grant: Close

Determinants of acquired resistance in small cell lung cancer

Open Date: 2016-04-18

Close Date: 2021-03-31

Grant: Close

Identification and validation of synthetic lethality in KRAS mutant lung adenocarcinoma patient derived xenografts

Open Date: 2015-08-01

Close Date: 2019-07-31

Grant: Close

Genetic and Epigenetic Determinants of Lung Cancer Subtype: Adenocarcinoma to Small Cell Conversion

Open Date: 2012-10-01

Close Date: 2013-09-01

Articles (18)

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Collaborators (12)

Deniz Demircioglu

Assistant Professor

Icahn School of Medicine at Mount Sinai

UNITED STATES

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Paul Romesser

Memorial Sloan Kettering Cancer Center

UNITED STATES

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Matthew Bott

Memorial Sloan Kettering Cancer Center

UNITED STATES

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Stephen Liu

Associate Professor

Georgetown University School of Medicine

UNITED STATES

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Christy Ralph

Clinical Associate Professor in Medical Oncology

University of Leeds

UNITED KINGDOM

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Memorial Sloan Kettering Cancer Center

UNITED STATES

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Vivek Verma

Faculty, Assistant Professor

University of Minnesota Hormel Institute

UNITED STATES

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Charles Rudin

Research Interests

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Recent Grants

Articles (18)

Senescence-directed nanotherapy ameliorates fibrosis and overcomes immune exclusion in cancer

Clinicogenomic analysis of EGFR-mutant lung tumors identifies Rb pathway inactivation as a hallmark of squamous transformation

Brief Report: Proposed Clinical Trial Guidelines Based on Clinicopathologic Heterogeneity of Metastatic Pulmonary Large Cell Neuroendocrine Carcinoma

Atezolizumab plus chemotherapy for Asian vs. non-Asian patients with extensive-stage small-cell lung cancer: A propensity score matched pooled analysis of four phase 3 trials

Clinical Responses to Tarlatamab Among Patients With Pulmonary Carcinoid

Development of Antibody–Drug Conjugates Targeting L1CAM to Treat Metastatic Cancer

Ifinatamab Deruxtecan in Patients With Extensive-Stage Small Cell Lung Cancer: Primary Analysis of the Phase II IDeate-Lung01 Trial

Dopamine D2 receptor agonists abrogate neuroendocrine tumour angiogenesis to inhibit chemotherapy-refractory small cell lung cancer progression

Seizure-Related Homolog Protein 6 (SEZ6): Biology and Therapeutic Target in Neuroendocrine Carcinomas

SKYSCRAPER-02: Tiragolumab in Combination With Atezolizumab Plus Chemotherapy in Untreated Extensive-Stage Small-Cell Lung Cancer

Small cell lung cancer profiling: an updated synthesis of subtypes, vulnerabilities, and plasticity

Phase 1, open-label, dose-escalation study on the safety, pharmacokinetics, and preliminary efficacy of intravenous Coxsackievirus A21 (V937), with or without pembrolizumab, in patients with advanced solid tumors

De Novo and Histologically Transformed Small-Cell Lung Cancer Is Sensitive to Lurbinectedin Treatment Through the Modulation of EMT and NOTCH Signaling Pathways.

Tarlatamab: New Star on the Horizon for Small-Cell Lung Cancer?

Breathing room – focusing on the ‘other’ lung cancer

IL-18–secreting CAR T cells targeting DLL3 are highly effective in small cell lung cancer models

Clinical benefit from immunotherapy in patients with small cell lung cancer is associated with tumor capacity for antigen presentation

Neuroendocrine neoplasms of the lung and gastrointestinal system: convergent biology and a path to better therapies

Collaborators (12)

Deniz Demircioglu

Paul Romesser

Matthew Bott

Stephen Liu

Christy Ralph

Emelie Gezelius

Maria Skamagki

Luke Hoeppner

Xueqian Zhuang

Sk. Kayum Alam

Helena A. Yu

Vivek Verma

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