Charlotte Smith

Institut Necker-Enfants Malades

France

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Articles (13)

Year:

2025

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2025

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2025

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2024

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2024

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2023

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2023

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2023

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2023

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2022

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2021

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2021

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2020

Collaborators (6)

Nicolas Boissel

Université Paris Cité

FRANCE

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Lisa Russell

Senior Lecturer in Childhood Cancer and Haematology

Newcastle University

UNITED KINGDOM

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Salvatore Spicuglia

FRANCE

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Daniel Rico

Lecturer in Computational Biology

Newcastle University

UNITED KINGDOM

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Pavlo Lutsik

Assistant professor

KU Leuven

BELGIUM

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Simonin Mathieu

Institut Necker-Enfants Malades

FRANCE

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Charlotte Smith

Research Interests

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Articles (13)

Towards methylation-based redefinition of TAL1 positive T-cell acute lymphoblastic leukaemia (T-ALL)

Surface pTα expression predicts LCK activation and preclinical synergy of LCK and JAK coinhibition in adult T-ALL

Neo‐enhancers in T‐cell acute lymphoblastic Leukaemia (T‐ALL) and beyond

PHF6-altered T-ALL Harbor Epigenetic Repressive Switch at Bivalent Promoters and Respond to 5-Azacitidine and Venetoclax

DNA methylation as a new tool for the differential diagnosis between T-LBL and lymphocyte-rich thymoma

Harnessing the MYB-dependent TAL1 5'super-enhancer for targeted therapy in T-ALL.

IL-7 receptor expression is frequent in T-cell acute lymphoblastic leukemia and predicts sensitivity to JAK inhibition

TAL1 activation in T-Cell acute lymphoblastic leukemia: A novel oncogenic 3' neoenhancer.

TREC mediated oncogenesis in human immature T lymphoid malignancies preferentially involves ZFP36L2

Dynamics of broad H3K4me3 domains uncover an epigenetic switch between cell identity and cancer-related genes

Epigenetic analysis of patients with T-ALL identifies poor outcomes and a hypomethylating agent-responsive subgroup

PRC2 loss of function confers a targetable vulnerability to BET proteins in T-ALL.

Blueprint of human thymopoiesis reveals molecular mechanisms of stage-specific TCR enhancer activation.

Collaborators (6)

Nicolas Boissel

Lisa Russell

Salvatore Spicuglia

Daniel Rico

Pavlo Lutsik

Simonin Mathieu

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