Christian Klein

Ruprecht Karls Universität Heidelberg

Germany

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Articles (10)

Year:

2023

Year:

2022

Year:

2022

Year:

2022

Year:

2021

Year:

2021

Year:

2021

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2021

Year:

2021

Year:

2020

Collaborators (4)

Mila-Mareen Leuthold

Heidelberg University

GERMANY

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Branimir Bertoša

CROATIA

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Saverio Minucci

European Institute of Oncology

ITALY

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Nikos Kühl

GERMANY

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Christian Klein

Research Interests

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Articles (10)

N-sulfonyl peptide-hybrids as a new class of dengue virus protease inhibitors

Discovery of potent benzoxaborole inhibitors against SARS-CoV-2 main and dengue virus proteases

Corona versus Dengue: Distinct Mechanisms for Inhibition of Polyprotein Processing by Antiviral Drugs

Insights into the design of inhibitors of the EGFR family with anticancer activity overcoming resistance: A case of optimizing thieno[2,3-d]pyrimidine-based EGFR inhibitors

On track to tackle dengue: History and future of NS4B ligands.

Inhibitor potency and assay conditions: A case study on SARS-CoV-2 main protease.

The spectrum between substrates and inhibitors: Pinpointing the binding mode of dengue protease ligands with modulated basicity and hydrophobicity.

Efficiency Improvements and Discovery of New Substrates for a SARS-CoV-2 Main Protease FRET Assay.

Beyond Basicity: Discovery of Nonbasic DENV-2 Protease Inhibitors with Potent Activity in Cell Culture.

Correction to Peptide-β-lactam Inhibitors of Dengue and West Nile Virus NS2B-NS3 Protease Display Two Distinct Binding Modes.

Collaborators (4)

Mila-Mareen Leuthold

Branimir Bertoša

Saverio Minucci

Nikos Kühl

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