Christine Helsen

Vrije Universiteit Brussel

Belgium

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Articles (13)

Year:

2025

Year:

2024

Year:

2024

Year:

2024

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2023

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2022

Year:

2022

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2022

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2022

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2022

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2022

Year:

2021

Year:

2020

Collaborators (8)

Joost Schymkowitz

Professor

Katholieke Universiteit Leuven

BELGIUM

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Nikolaos Louros

Assistant Professor

University of Texas Southwestern Medical Center

UNITED STATES

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Vanessa Dubois

Professor

Ghent University

BELGIUM

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Jorma Palvimo

Professor of Medical Biochemisty

University of Eastern Finland

FINLAND

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Anne Rochtus

University Hospitals Leuven

BELGIUM

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Diether Lambrechts

full professor

KU Leuven

BELGIUM

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Martin van Royen

Assistant Professor

Erasmus MC

NETHERLANDS

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Bart Ghesquière

Associate Professor

KU Leuven

BELGIUM

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Christine Helsen

Research Interests

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Articles (13)

Androgens differentially modulate glucocorticoid effects on adipose tissue and lean mass

Structural mechanism underlying variations in DNA binding by the androgen receptor

Discovery of a novel androgen receptor antagonist, MEL-6, with stereoselective activity and optimization of its metabolic stability

Rational evolution for altering the ligand preference of estrogen receptor alpha

Study of novel androgen receptor V770 variant in androgen insensitivity syndrome patients reveals the transitional state of the androgen receptor ligand binding domain homodimer

Exploiting Ligand-binding Domain Dimerization for Development of Novel Androgen Receptor Inhibitors

Antizyme Inhibitor 1 Regulates Matrikine Expression and Enhances the Metastatic Potential of Aggressive Primary Prostate Cancer

N/C Interactions Are Dispensable for Normal In Vivo Functioning of the Androgen Receptor in Male Mice

A disease-associated missense mutation in CYP4F3 affects the metabolism of leukotriene B4 via disruption of electron transfer

Small-molecule profiling for steroid receptor activity using a universal steroid receptor reporter assay

The T850D Phosphomimetic Mutation in the Androgen Receptor Ligand Binding Domain Enhances Recruitment at Activation Function 2

The androgen receptor depends on ligand‐binding domain dimerization for transcriptional activation

A Mechanistic High-Content Analysis Assay Using a Chimeric Androgen Receptor That Rapidly Characterizes Androgenic Chemicals

Collaborators (8)

Joost Schymkowitz

Nikolaos Louros

Vanessa Dubois

Jorma Palvimo

Anne Rochtus

Diether Lambrechts

Martin van Royen

Bart Ghesquière

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