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Christine Roffe

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Professor of Stroke Medicine

Keele University

United Kingdom

Research Interests

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Recent Grants

Grant: Close

A randomised controlled trial of the effectiveness of surface neuromuscular stimulation using the geko™ device compared with intermittent pneumatic compression to prevent venous thromboembolism in immobile acute stroke patients

Open Date: 2022-08-01

Close Date: 2025-07-31

Grant: Close

The Metoclopramide for Avoiding Pneumonia after Stroke (MAPS-2) Trial: a single-blind randomized controlled trial of metoclopramide for the prevention of pneumonia in patients with dysphagia after an acute stroke

Open Date: 2021-05-01

Close Date: 2025-04-30

Grant: Close

The Metoclopramide and selective oral decontamination for Avoiding Pneumonia after Stroke (MAPS-2) Trial: a 2x2 double-blind, randomized controlled trial of metoclopramide and selective oral decontamination for the prevention of pneumonia in patients with dysphagia after an acute stroke

Open Date: 2016-07-01

Close Date: 2019-01-31

Grant: Close

The Stroke Oxygen Study: a multi-centre prospective randomised open blinded-endpoint study to assess whether routine oxygen treatment in the first 72 hours after a stroke improves long-term outcome

Open Date: 2011-09-01

Close Date: 2015-06-30

Grant: Close

The Stroke Oxygen Supplementation (SOS) study

Open Date: 2008-09-01

Close Date: 2011-08-31

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Collaborators (26)

Catherine Emma Davidson

Research Associate

University of Central Lancashire

UNITED KINGDOM

Christine Roffe

Research Interests

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Recent Grants

Articles (20)

European stroke organisation guideline on stroke-associated pneumonia

Baseline characteristics of patients recruited to the mannitol for cerebral oedema after acute intracerebral haemorrhage (MACE-ICH) trial.

Reperfusion treatment in basilar artery occlusion presenting with mild symptoms

Association of Smoking and Young Cryptogenic Ischemic Stroke

Thrombolysis With Tenecteplase for Minor Disabling Stroke: Secondary Analysis of the TEMPO-2 Randomized Clinical Trial.

Mannitol for cerebral oedema after acute intracerebral haemorrhage (MACE-ICH): protocol for a prospective, randomised, open-label, blinded-endpoint phase IIb trial.

Preventing Embolization to a New Vascular Territory: An in Vitro Study Exploring Alternative Techniques for Dual-Stent-Retriever Cerebral Thrombectomy.

Cerebrovascular Pressure Restoration Rates during Recanalisation with Aspiration and Stent-Retriever Thrombectomy for Acute Ischaemic Stroke: An in Vitro Study

Evaluating methods of detecting and determining the type of urinary incontinence in adults after stroke: A systematic review

Outcome 1 year after ICH: Data from the Tranexamic acid for IntraCerebral Haemorrhage 2 (TICH-2) trial.

The Effect of Tranexamic Acid on Neurosurgical Intervention in Spontaneous Intracerebral Hematoma: Data From 121 Surgically Treated Participants From the Tranexamic Acid in IntraCerebral Hemorrhage-2 Randomized Controlled Trial

Pre-hospital transdermal glyceryl trinitrate for transient ischaemic attack: Data from the RIGHT-2 trial.

Department of Error

Is intraprocedural intravenous aspirin safe for patients who require emergent extracranial stenting during mechanical thrombectomy?

Adult-onset mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes (MELAS): a diagnostic challenge

Effects of blood pressure and tranexamic acid in spontaneous intracerebral haemorrhage: A secondary analysis of a large randomised controlled trial

Prehospital transdermal glyceryl trinitrate for ultra-acute ischaemic stroke: data from the RIGHT-2 randomised sham-controlled ambulance trial.

Reperfusion by endovascular thrombectomy and early cerebral edema in anterior circulation stroke: Results from the SITS-International Stroke Thrombectomy Registry

Cerebral edema in intracerebral hemorrhage

The effect of distal aspiration catheter position on collateral flow in mechanical thrombectomy – an <i>in vitro</i> study

Collaborators (26)

Catherine Emma Davidson

Marius Matusevicius

Georgios Tsivgoulis

Simone Beretta

Jason Appleton

Rustam Al-Shahi Salman

Andrew Clegg

Kailash Krishnan

Elizabeth Lightbody

Thompson Robinson

Andreas Meisel

Mena Farag

Houman Khosravani

Craig J Smith

Kausik Chatterjee

Robert Dineen

Irene Escudero-Martínez

Cath Harris

Michal Karlinski

Tomasz Dziedzic

Anna Podlasek

Mary Joan Macleod

Grant Mair

Ram Bajpai

Joanne Booth

Azlinawati Ali

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