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Christof Lenz

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Director Core Facility Proteomics

University Medical Center Göttingen

Germany

Research Interests

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Recent Grants

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Mass spectrometry Service (Z02)

Open Date: 2023-01-01

Close Date:

Grant: Close

GRK 2824: Heart and brain diseases: integrative research across organs

Open Date: 2023-01-01

Close Date:

Grant: Close

A premotor disease signature for ALS (premodiALS)

Open Date: 2022-12-01

Close Date: 2025-11-30

Grant: Close

High resolution proteomics mass spectrometer with ion mobility interface coupled to nanoLC

Open Date: 2022-01-01

Close Date:

Grant: Close

High resolution electrospray ionization tandem mass spectrometer coupled to nanoflow chromatography for proteome research

Open Date: 2020-01-01

Close Date:

Articles (20)

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Collaborators (23)

Ulrich Sax

Univ-Prof. Dr., Head of Translational Research Informatics Research Group

Universitätsmedizin Göttingen

GERMANY

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Olaf Jahn

Max Planck Institute for Multidisciplinary Sciences

GERMANY

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Lars V. Bock

Max Planck Institute for Multidisciplinary Sciences

GERMANY

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Emma Fenech

Group Leader

University of Cologne

GERMANY

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University of Melbourne

AUSTRALIA

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Inês Castro

Assistant Professor

New College of the Humanities

UNITED KINGDOM

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Nelson Dusetti

Cancer Research Center of Marseille

INSERM Délégation régionale Provence Alpes Cote d'Azur et Corse

FRANCE

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Satadru Lahiri

Assistant Professor

Baylor College of Medicine

UNITED STATES

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Laura Kremer

University Medical Center Göttingen

GERMANY

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Professor of Biochemistry

GERMANY

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Emiel P. C. van der Vorst

Research Group Leader

RWTH Aachen University

GERMANY

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Phillipp Brockmeyer

Medical Doctor/Dentist

University Medical Center Goettingen

GERMANY

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Christof Lenz

Research Interests

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Recent Grants

Articles (20)

Targeting Interleukin-8-Mediated Cellular Crosstalk Reverses Hypertrophic Cardiomyopathy and Cardiac Fibrosis in Noonan Syndrome

VAPA at the inner nuclear membrane affects nuclear lamins and nuclear morphology

Selective ubiquitination of drug-like small molecules by the ubiquitin ligase HUWE1

Identification of a presymptomatic and early disease signature for amyotrophic lateral sclerosis (ALS)

SMIM20 promotes complex IV biogenesis and Ca2+ signaling in mice heart

PP2A-B56α is a key determinant of cardiac protein phosphorylation and functional responses to β-adrenergic signalling

The Ceramide-Dependent EV Secretome Differentially Affects Prostate Cancer Cell Migration

Profiling the LAM Family of Contact Site Tethers Provides Insights into Their Regulation and Function

Proteomic Exploration of L1CAM+-Extracellular Vesicles from Plasma of Manifest and Prodromal Parkinson’s Disease

Identification and validation of a tear fluid-derived protein biomarker signature in patients with amyotrophic lateral sclerosis

More than myocytes: The heart's electrical ensemble

TP53 missense-specific transcriptional plasticity drives resistance against cell cycle inhibitors in pancreatic cancer

Dysferlin Enables Tubular Membrane Proliferation in Cardiac Hypertrophy.

Proteome profiling of Campylobacter jejuni 81–176 at 37 °C and 42 °C by label-free mass spectrometry

Targeting calpain-2-mediated junctophilin-2 cleavage delays heart failure progression following myocardial infarction.

Skin microdialysis detects distinct immunologic patterns in chronic inflammatory skin diseases

Unbiased complexome profiling and global proteomics analysis reveals mitochondrial impairment and potential changes at the intercalated disk in presymptomatic R14Δ/+ mice hearts

Iron starvation results in up-regulation of a probable Haloferax volcanii siderophore transporter

mini-Complexome Profiling (mCP), an FDR-controlled workflow for global targeted detection of protein complexes

Author Correction: Single-cell transcriptomics reveal extracellular vesicles secretion with a cardiomyocyte proteostasis signature during pathological remodeling

Collaborators (23)

Ulrich Sax

Olaf Jahn

Lars V. Bock

Emma Fenech

Wolfgang Bohne

Giulia Germena

Yanlong Ji

Michael Menden

Inês Castro

Nelson Dusetti

Satadru Lahiri

Laura Kremer

Mary-Louise Rogers

Mario Pavez-Giani

Martin Schmelz

Michael Bartl

Bernd Wollnik

Matthias Gehringer

Yuriana Aguilar-Sanchez

Ramona Schulz-Heddergott

Julia Christina Gross

Emiel P. C. van der Vorst

Phillipp Brockmeyer

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