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Christoph Hölscher

Research Center Borstel - Leibniz Lung Center

Germany

Research Interests

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Professors in Germany

Articles (6)

Year:

2025

Year:

2025

Year:

2025

Year:

2025

Year:

2024

Year:

2023

Collaborators (5)

Dominik Schwudke

Research Center Borstel - Leibniz Lung Center

GERMANY

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Christoph Lange

Research Center Borstel - Leibniz Lung Center

GERMANY

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Rob Christiaan van Wijk

Assistant professor / Principal investigator "Translational Immuno-Pharmacology"

Leiden University

NETHERLANDS

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Norbert Heinrich

Scientific Lead TB

LMU University Hospital

GERMANY

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Andreas Römpp

University of Bayreuth

GERMANY

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Christoph Hölscher

Research Interests

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Articles (6)

The clinical-stage drug BTZ-043 accumulates in murine tuberculosis lesions and efficiently acts against Mycobacterium tuberculosis.

The molecular bacterial load assay predicts treatment responses in patients with pre-XDR/XDR-tuberculosis more accurately than GeneXpert Ultra MTB/Rif

C1q and mannose-binding lectin binding and complement activation across genetically diverse Mycobacterium tuberculosis complex strains.

Translational modeling of BTZ-043 in predicting phase IIA efficacy and evaluating drug-drug interactions with BPaL in murine models.

Investigating the treatment shortening potential of a combination of bedaquiline, delamanid and moxifloxacin with and without sutezolid, in a murine tuberculosis model with confirmed drug exposures.

Whole cell hydride Meisenheimer complex biotransformation guided optimization of antimycobacterial benzothiazinones.

Collaborators (5)

Dominik Schwudke

Christoph Lange

Rob Christiaan van Wijk

Norbert Heinrich

Andreas Römpp

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