Christopher Cairo

Professor

University of Alberta

Canada

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Professor Christopher Cairo is a faculty member at the University of Alberta in Canada. His research focuses on glycobiology, specifically in relation to neuraminidase enzymes and their roles in various neurological and hematological conditions. His recent publications explore CNS pathology in metabolic disorders, strategies for neoglycoconjugate synthesis, and the development of selective inhibitors for human neuraminidase 1.

Articles (18)

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2025

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2021

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2021

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2020

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2020

Collaborators (3)

Erik Lillehoj

Associate Professor

University of Maryland School of Medicine

UNITED STATES

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Antoine Caillon

Assistant Professor

University of Montreal

CANADA

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Alexey V. Pshezhetsky

Université de Montréal

CANADA

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Christopher Cairo

Research Interests

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About

Articles (18)

Neuraminidase 1 secondary deficiency contributes to CNS pathology in neurological mucopolysaccharidoses via brain protein hypersialylation

A Mild Protecting-Group Free Strategy for Neoglycoconjugate Synthesis

Improved C5‐Amide Bioisosteres for Human Neuraminidase 1 Inhibitors Based on 2‐Deoxy‐2,3‐Didehydro‐N‐Acetyl Neuraminic Acid

Bioisosteres at C9 of 2-Deoxy-2,3-didehydro-N-acetyl Neuraminic Acid Identify Selective Inhibitors of NEU3

Convergent synthesis of a hexadecavalent heterobifunctional ABO blood group glycoconjugate

Facile synthesis of C5-azido derivatives of thiosialosides and 2,3-dehydro-5-N-acetylneuraminic acid (DANA)

Detection Strategies for Sialic Acid and Sialoglycoconjugates

Severe kidney dysfunction in sialidosis mice reveals an essential role for neuraminidase 1 in reabsorption

New insights into the glycobiology of immune thrombocytopenia

NEU1 and NEU3 enzymes alter CD22 organization on B cells

The Janus‐like role of neuraminidase isoenzymes in inflammation

The Janus‐like role of neuraminidase isoenzymes in inflammation

Extending the in vivo persistence of synthetic glycoconjugates using a serum-protein binder

Profiling of glycosphingolipids with SCDase digestion and HPLC-FLD-MS

Characterization of ABH‐subtype donor‐specific antibodies in ABO‐A‐incompatible kidney transplantation

Neuraminidases 1 and 3 Trigger Atherosclerosis by Desialylating Low-Density Lipoproteins and Increasing Their Uptake by Macrophages.

Therapeutic Effect of Neuraminidase-1-Selective Inhibition in Mouse Models of Bleomycin-Induced Pulmonary Inflammation and Fibrosis.

Human neuraminidases have reduced activity towards modified sialic acids on glycoproteins

Collaborators (3)

Erik Lillehoj

Antoine Caillon

Alexey V. Pshezhetsky

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