Christopher LaRock

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Associate professor

Emory University

United States

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About

Christopher LaRock is an Associate Professor at Emory University in the United States. His research focuses on the therapeutic inhibition of metalloproteases, interactions between Group A Streptococcus and the host, and advanced methodologies in nanomedicine. Recent publications highlight his work on bacterial virulence, bioprinting of hydrogels, and inflammation in response to bacterial infections.

Recent Grants

Grant: Open

Keratinocyte pyroptosis guards against invasive bacteria

Open Date: 2022-01-01

Close Date: 2027-01-01

Grant: Close

Proteolytic regulation of the Streptococcus pyogenes cell surface

Open Date: 2021-01-15

Close Date: 2025-12-31

Grant: Close

IL-1 regulation of group A Streptococcus infection

Open Date: 2018-04-09

Close Date: 2020-03-31

Articles (19)

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2021

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2021

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2021

Collaborators (5)

John K. McCormick

University of Western Ontario

CANADA

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Doris LaRock

Emory University School of Medicine

UNITED STATES

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Steven Zanganeh

UNITED STATES

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Mohammadreza Shokouhimehr

Seoul National University

SOUTH KOREA

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Vahid Serpooshan

UNITED STATES

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Christopher LaRock

Research Interests

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About

Recent Grants

Articles (19)

Therapeutic Inhibition of Metalloproteases by Tetracyclines During Infection by Multidrug-Resistant Pseudomonas

Pentamidine inhibition of streptopain attenuates Streptococcus pyogenes virulence

Proinflammatory synergy between protease and superantigen streptococcal pyogenic exotoxins

Protocol for 3D bioprinting of nanoparticle-laden hydrogels to enhance antibacterial and imaging properties.

Improved Methodology for Evaluating Nanomedicine Antibacterial Properties in Biological Fluids

Group A Streptococcus interactions with the host across time and space

Engineered probiotic overcomes pathogen defences using signal interference and antibiotic production to treat infection in mice

Human microglial cells as a therapeutic target in a neurodevelopmental disease model

Constitutive secretion of pro-IL-18 allows keratinocytes to initiate inflammation during bacterial infection

Chemical Optimization of Selective Pseudomonas aeruginosa LasB Elastase Inhibitors and Their Impact on LasB-Mediated Activation of IL-1β in Cellular and Animal Infection Models

Assessing Interleukin-1β Activation During Pyroptosis.

Detoxification of reactive oxygen species by the hyaluronic acid capsule of group A Streptococcus

3D bioprinting of nanoparticle-laden hydrogel scaffolds with enhanced antibacterial and imaging properties

Group A Streptococcus induces GSDMA-dependent pyroptosis in keratinocytes

Antibiotic Treatment, Mechanisms for Failure, and Adjunctive Therapies for Infections by Group A <i>Streptococcus</i>.

Playing With Fire: Proinflammatory Virulence Mechanisms of Group A <i>Streptococcus</i>.

Restoring Endogenous Repair Mechanisms to Heal Chronic Wounds with a Multifunctional Wound Dressing.

Opportunistic Invasive Infection by Group A Streptococcus During Anti–Interleukin-6 Immunotherapy

3D Bioprinted Bacteriostatic Hyperelastic Bone Scaffold for Damage-Specific Bone Regeneration

Collaborators (5)

John K. McCormick

Doris LaRock

Steven Zanganeh

Mohammadreza Shokouhimehr

Vahid Serpooshan

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