Christy Hom

Associate Clinical Professor

University of California

United States

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Christy Hom is an Associate Clinical Professor at the University of California, specializing in neurodegenerative diseases, particularly Alzheimer's disease in individuals with Down syndrome. Her recent research includes investigating the relationship between brain structure and neuropathological burden, as well as the effects of genetic and biological markers on cognitive function. With a focus on resilience and symptoms related to dementia in adults with Down syndrome, her work contributes to understanding the complexities of Alzheimer's disease within this population.

Articles (10)

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2025

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2025

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2024

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2024

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2024

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2024

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2024

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2024

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2024

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2024

Collaborators (2)

Brian Gordon

Assistant Professor

Washington University in Saint Louis School of Medicine

UNITED STATES

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Henry Paulson

University of Michigan

UNITED STATES

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Christy Hom

Research Interests

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Articles (10)

Correlating hippocampal and amygdala volumes with neuropathological burden in Down syndrome and Alzheimer's disease and related neurodegenerative pathologies using 7T postmortem MRI.

A neuropathology case report of a woman with Down syndrome who remained cognitively stable: Implications for resilience to neuropathology.

Whole genome-wide sequence analysis of long-lived families (Long-Life Family Study) identifies MTUS2 gene associated with late-onset Alzheimer's disease.

Comparison of tau spread in people with Down syndrome versus autosomal-dominant Alzheimer's disease: a cross-sectional study

Timeline to symptomatic Alzheimer's disease in people with Down syndrome as assessed by amyloid-PET and tau-PET: a longitudinal cohort study.

The effects of mosaicism on biological and clinical markers of Alzheimer's disease in adults with Down syndrome.

Cerebrovascular disease is associated with Alzheimer's plasma biomarker concentrations in adults with Down syndrome.

A pathway linking pulse pressure to dementia in adults with Down syndrome.

Cognitive and functional performance and plasma biomarkers of early Alzheimer's disease in Down syndrome.

Insomnia Symptoms Are Associated with Measures of Functional Deterioration and Dementia Status in Adults with Down Syndrome at High Risk for Alzheimer's Disease.

Collaborators (2)

Brian Gordon

Henry Paulson

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