Christy Trussoni

Assistant Professor of Medicine

Mayo Clinic

United States

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About

Christy Trussoni is an Assistant Professor of Medicine at Mayo Clinic in the United States. Her research focuses on immunotherapy outcomes in metastatic colorectal cancer, cholestatic liver diseases, and the role of cellular senescence in immunopathology. Recent articles co-authored by Dr. Trussoni explore topics such as hepatic cystogenesis, the influence of the aged immune system, and the effects of reactive cholangiocytes in primary sclerosing cholangitis.

Articles (9)

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2025

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2023

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2022

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2021

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2021

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2021

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2020

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2020

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2020

Collaborators (2)

Yi Zhu

Assistant Professor

Mayo Clinic

UNITED STATES

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Tokio Sano

Tufts University

UNITED STATES

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Christy Trussoni

Research Interests

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Articles (9)

Spatially Resolved, Multiregion Proteomics for Prediction of Immunotherapy Outcome in Deficient Mismatch Repair Metastatic Colorectal Cancer

Macrophages make a difference in cholestatic liver diseases – but how?

Cellular senescence in the cholangiopathies: a driver of immunopathology and a novel therapeutic target.

An aged immune system drives senescence and ageing of solid organs.

Autophagy promotes hepatic cystogenesis in polycystic liver disease by depletion of cholangiocyte ciliogenic proteins.

Autophagy-mediated reduction of miR-345 contributes to hepatic cystogenesis in polycystic liver disease.

Senescent cholangiocytes release extracellular vesicles that alter target cell phenotype via the epidermal growth factor receptor.

Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Receptor Deficiency Promotes the Ductular Reaction, Macrophage Accumulation, and Hepatic Fibrosis in the Abcb4<sup>-/-</sup> Mouse.

The Spectrum of Reactive Cholangiocytes in Primary Sclerosing Cholangitis.

Collaborators (2)

Yi Zhu

Tokio Sano

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