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Chun-Li Zhang

Professor

University of Texas Southwestern Medical Center

United States

Research Interests

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About

Chun-Li Zhang is a Professor at The University of Texas Southwestern Medical Center, USA. His research primarily focuses on traumatic brain injury, neurodegeneration, and spinal cord repair, as evidenced by his recent articles exploring the roles of MAP4Ks and glial cell reprogramming. Professor Zhang contributes significantly to the understanding of glial responses and potential therapeutic avenues for neurodegenerative diseases, particularly amyotrophic lateral sclerosis.

Articles (19)

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2020

Collaborators (6)

Yuqing Li

Professor of Neurology and Neuroscience

University of Florida

UNITED STATES

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Bo Chen

Assistant Professor

University of Texas Medical Branch

UNITED STATES

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Allan-Hermann Pool

Assistant Professor

University of Texas Southwestern Medical Center

UNITED STATES

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Shu G. Chen

Professor

The University of Alabama

UNITED STATES

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Anupam Raina

University of Alabama, Tuscaloosa

UNITED STATES

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Baojin Ding

Associate Professor with Tenure

LSU Health Shreveport

UNITED STATES

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Chun-Li Zhang

Research Interests

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About

Articles (19)

Skin-derived α-synuclein strains from PD, DLB, and MSA induce distinct intracellular pathology and neurodegeneration

Dysregulated nuclear Lamin B1 in DYT1 dystonia thickens nuclear lamina and disrupts 14-3-3 proteins

Phosphorylation and DNA damage resolution coordinate SOX2-mediated reprogramming in vivo

Unbiased quantification of persistent postural and motor deficits following spinal cord injury in mice

In vivo reprogramming of NG2 glia improves bladder function after spinal cord injury

The Citron homology domain of MAP4Ks improves outcomes of traumatic brain injury

GADD45G operates as a pathological sensor orchestrating reactive gliosis and neurodegeneration

Simple and highly specific targeting of resident microglia with adeno-associated virus

MAP4K inhibition as a potential therapy for amyotrophic lateral sclerosis

NG2 glia reprogramming induces robust axonal regeneration after spinal cord injury

Screens in aging-relevant human ALS-motor neurons identify MAP4Ks as therapeutic targets for the disease

In vivo cell fate reprogramming for spinal cord repair

In vivo glia‐to‐neuron conversion: pitfalls and solutions

Reply to In vivo confusion over in vivo conversion

NEK6 is an injury‐responsive kinase cooperating with STAT3 in regulation of reactive astrogliosis

Revisiting astrocyte to neuron conversion with lineage tracing in vivo

Disease Modeling with Human Neurons Reveals LMNB1 Dysregulation Underlying DYT1 Dystonia

Aging-relevant human basal forebrain cholinergic neurons as a cell model for Alzheimer’s disease

Therapeutic Nanomaterials for Neurological Diseases and Cancer Therapy

Collaborators (6)

Yuqing Li

Bo Chen

Allan-Hermann Pool

Shu G. Chen

Anupam Raina

Baojin Ding

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