Chun-Liang Chen

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Purdue University

United States

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Structural and Functional Analysis of Phosphatidylinositol 3-Kinase Gamma

Open Date: 2021-04-01

Close Date: 2023-03-31

Articles (9)

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2024

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2024

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2024

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2024

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2022

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2022

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2021

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2020

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2020

Collaborators (4)

Cynthia Stauffacher

Purdue University

UNITED STATES

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Carmen Dessauer

Professor and Vice-Chair

The University of Texas Health Science Center at Houston

UNITED STATES

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Qing Deng

Associate Professor

Purdue University

UNITED STATES

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Xin-Qiu Yao

Assistant Professor

University of Nebraska Omaha

UNITED STATES

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Chun-Liang Chen

Research Interests

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Contact this professor

Recent Grants

Articles (9)

Structure of adenylyl cyclase 5 in complex with Gβγ offers insights into ADCY5-related dyskinesia

Molecular basis for Gβγ-mediated activation of phosphoinositide 3-kinase γ

Structural and dynamic changes in P-Rex1 upon activation by PIP3 and inhibition by IP4

Structural and dynamic changes in P-Rex1 upon activation by PIP3 and inhibition by IP4

Cryo-EM structures of alphavirus conformational intermediates in low pH–triggered prefusion states

Structural/functional studies of Trio provide insights into its configuration and show that conserved linker elements enhance its activity for Rac1.

Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1

Visualizing the enzyme mechanism of mevalonate diphosphate decarboxylase

Cryo-EM structure of eastern equine encephalitis virus in complex with heparan sulfate analogues.

Collaborators (4)

Cynthia Stauffacher

Carmen Dessauer

Qing Deng

Xin-Qiu Yao

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