Chunli Yu

Associate Professor

Icahn School of Medicine at Mount Sinai

United States

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Chunli Yu is an Associate Professor at the Icahn School of Medicine at Mount Sinai, USA. His research focuses on metabolic disorders, specifically relating to fatty acid oxidation, lysosomal enzyme activities, and mitochondrial functions. Recent publications include investigations into substrate reduction therapy for valine and isoleucine metabolism disorders and the impact of genetic variations on fat oxidation in HIV-infected children.

Articles (10)

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2023

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2022

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2022

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2022

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2022

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2021

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2021

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2021

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2021

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2020

Collaborators (2)

Frédéric M. Vaz

NETHERLANDS

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Natalya Pavlova

Assistant Professor

Huntsman Cancer Institute

UNITED STATES

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Chunli Yu

Research Interests

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Articles (10)

Acyl‐CoA dehydrogenase substrate promiscuity: Challenges and opportunities for development of substrate reduction therapy in disorders of valine and isoleucine metabolism

A mitochondrial long-chain fatty acid oxidation defect leads to transfer RNA uncharging and activation of the integrated stress response in the mouse heart

Acylcarnitines and Genetic Variation in Fat Oxidation Genes in HIV-infected, Antiretroviral-treated Children With and Without Myopathy

Characterization and structure of the human lysine-2-oxoglutarate reductase domain, a novel therapeutic target for treatment of glutaric aciduria type 1

Measurement of lysosomal enzyme activities: A technical standard of the American College of Medical Genetics and Genomics (ACMG)

Glutaric aciduria type 3 is a naturally occurring biochemical trait in inbred mice of 129 substrains

Murine deficiency of peroxisomal l-bifunctional protein (EHHADH) causes medium-chain 3-hydroxydicarboxylic aciduria and perturbs hepatic cholesterol homeostasis

Plasma lyso-sphingomyelin levels are positively associated with clinical severity in acid sphingomyelinase deficiency

The peroxisomal transporter ABCD3 plays a major role in hepatic dicarboxylic fatty acid metabolism and lipid homeostasis

DHTKD1 and OGDH display substrate overlap in cultured cells and form a hybrid 2-oxo acid dehydrogenase complex in vivo

Collaborators (2)

Frédéric M. Vaz

Natalya Pavlova

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