Claudia dos Santos

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Associate Professor of Medicine

University of Toronto

Canada

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About

Claudia dos Santos is an Associate Professor of Medicine at the University of Toronto, Canada. Her research areas encompass innate immune response, infectious disease diagnostics, and microRNA-based therapies, with recent publications highlighting advancements in the understanding of caspase-8 functions, antibody detection methods, and critical illness responses in patients. Her work also emphasizes equity and diversity in critical care practices, showcasing the impact of such initiatives on patient outcomes.

Recent Grants

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Molecular Mechanism(s) of Lung Protection from Ventilator Induced Lung Injury (VILI)

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UNITED STATES

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Duncan Stewart

Professor

University of Ottawa

CANADA

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Filio Billia

University Health Network

CANADA

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Monika Gora

Institute of Biochemistry and Biophysics, Polish Academy of Sciences

POLAND

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Claudia dos Santos

Research Interests

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About

Recent Grants

Articles (20)

Caspase-8: Arbitrating Life and Death in the Innate Immune System

Development of a broadly adaptable TR-FRET serological assay for sensitive and specific detection of infectious disease antibodies in human sera

Tiny Guides, Big Impact: Focus on the Opportunities and Challenges of miR-Based Treatments for ARDS

Pre-Clinical Studies of MicroRNA-Based Therapies for Sepsis: A Scoping Review

Reply: Mesenchymal stromal (stem) cell therapy modulates miR-193b-5p expression to attenuate sepsis-induced acute lung injury

Canadian Critical Care Society position statement on Equity, Diversity, Decolonization, and Inclusion,Énoncé de position de la Société canadienne de soins intensifs sur l’équité, la diversité, l’inclusion et la décolonisation

Distinct host-response signatures in circulatory shock: a narrative review

Extracellular Vesicles from Different Sources of Mesenchymal Stromal Cells Have Distinct Effects on Lung and Distal Organs in Experimental Sepsis

Validation of reference gene stability for miRNA quantification by reverse transcription quantitative PCR in the peripheral blood of patients with COVID-19 critical illness.

Preventing occludin tight-junction disruption via inhibition of microRNA-193b-5p attenuates viral load and influenza-induced lung injury.

Mitochondria and cytochrome components released into the plasma of severe COVID-19 and ICU acute respiratory distress syndrome patients.

MicroRNA regulatory networks associated with abnormal muscle repair in survivors of critical illness

Role of miRNA dysregulation in sepsis

Diversity in the Expressed Genomic Host Response to Myocardial Infarction

A longitudinal study of alterations of circulating DJ-1 and miR203a-3p in association to olanzapine medication in a sample of first episode patients with schizophrenia

COVID-19 bimodal clinical and pathological phenotypes

Cardiovascular signatures of COVID-19 predict mortality and identify barrier stabilizing therapies

Comprehensive multi-cohort transcriptional meta-analysis of muscle diseases identifies a signature of disease severity

DJ-1 binds to Rubicon to Impair LC-3 Associated Phagocytosis

Identifying clinical subtypes in sepsis-survivors with different one-year outcomes: a secondary latent class analysis of the FROG-ICU cohort

Collaborators (8)

Slava Epelman

Margaret Herridge

Wael Haddara

Srinivas Murthy

Pedro Leme Silva

Duncan Stewart

Filio Billia

Monika Gora

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