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Claudio Bussi

The Francis Crick Institute

United Kingdom

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Research Interests

Immunology

70%

Cell Biology

60%

Macrophage Biology

60%

Covid-19

40%

Metabolic Biology

40%

Immune Response

30%

Autophagy

30%

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Recent Grants

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Mitochondrial function in human macrophage-Mycobacterium tuberculosis interactions

Open Date: 2019-04-01

Close Date: 2021-04-01

Grant: Close

EMBO short-term fellowship

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Autophagy modulates cytokine production in microglial cells

Open Date:

Close Date:

Grant: Close

JCS Travelling Fellowship

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Boehringer Ingelheim Fonds Travel Grant

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Articles15

Lysosomes drive the piecemeal removal of mitochondrial inner membrane

Article Link

Year:

2024

Physiologic medium renders human iPSC-derived macrophages permissive for M. tuberculosis by rewiring organelle function and metabolism

Article Link

Year:

2024

ATG7 and ATG14 restrict cytosolic and phagosomal Mycobacterium tuberculosis replication in human macrophages

Article Link

Year:

2023

Publisher Correction: Stress granules plug and stabilize damaged endolysosomal membranes

Article Link

Year:

2023

Peroxisomal ROS control cytosolic Mycobacterium tuberculosis replication in human macrophages

Article Link

Year:

2023

Stress granules plug and stabilize damaged endolysosomal membranes

Article Link

Year:

2023

Lysosomal damage drives mitochondrial proteome remodelling and reprograms macrophage immunometabolism

Article Link

Year:

2022

Visualizing Pyrazinamide Action by Live Single-Cell Imaging of Phagosome Acidification and Mycobacterium tuberculosis pH Homeostasis.

Article Link

Year:

2022

Immune responses following third COVID-19 vaccination are reduced in patients with hematological malignancies compared to patients with solid cancer

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Year:

2022

Systemic sterile induced-co-expression of IL-12 and IL-18 drive IFN-γ-dependent activation of microglia and recruitment of MHC-II-expressing inflammatory monocytes into the brain

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Year:

2022

Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: the CAPTURE study

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Year:

2021

Functional antibody and T cell immunity following SARS-CoV-2 infection, including by variants of concern, in patients with cancer: the CAPTURE study

Article Link

Year:

2021

Cytokine release syndrome in a patient with colorectal cancer after vaccination with BNT162b2

Article Link

Year:

2021

SARS-CoV-2 detection by a clinical diagnostic RT-LAMP assay

Article Link

Year:

2021

Clinical outcomes of COVID-19 in long-term care facilities for people with epilepsy

Article Link

Year:

2021

Collaborators21

Jimena Perez-Lloret

University College London

UNITED KINGDOM

Paula Ordonez

Teaching Fellow

Imperial College London

UNITED KINGDOM

Johnathan Canton

Assistant Professor

University of Calgary

CANADA

Julia Mitschke

University Medical Center Freiburg

GERMANY

Katalin Wilkinson

The Francis Crick Institute

UNITED KINGDOM

Joshua Wright

NEW ZEALAND

Fergus Rugg-Gunn

Consultant Neurologist and Honorary Senior Lecturer

UCL Institute of Neurology, University College London

UNITED KINGDOM

Maximiliano Gutierrez

The Francis Crick Institute

UNITED KINGDOM

Laure Botella

The Francis Crick Institute

UNITED KINGDOM

Michael Howell

The Francis Crick Institute

UNITED KINGDOM

Scott Shepherd

The Francis Crick Institute

UNITED KINGDOM

Rachel Ulferts

The Francis Crick Institute

UNITED KINGDOM

Dimitrios Evangelopoulos

Lecturer in Microbiology

University College London Eastman Dental Institute

UNITED KINGDOM

Graeme Hewitt

King’s College London

UNITED KINGDOM

Mariana Silva dos Santos

Deputy Head of Metabolomics

The Francis Crick Institute

UNITED KINGDOM

Adam Sateriale

The Francis Crick Institute

UNITED KINGDOM

Thomas Reinheckel

Professor

University of Freiburg

GERMANY

Amin Oomatia

University College London

UNITED KINGDOM

Abhinay Ramaprasad

University of Glasgow

UNITED KINGDOM

Andela Saric

Assistant Professor

Institute of Science and Technology Austria

AUSTRIA

Enzo Z. Poirier

PSL Research University

FRANCE

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