Claudio Sorio

Associate professor

Università degli Studi della Campania Luigi Vanvitelli Scuola di Medicina e Chirurgia

Italy

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Claudio Sorio is an Associate Professor at Universita degli Studi di Verona Scuola di Medicina e Chirurgia in Italy. His research primarily focuses on cystic fibrosis, particularly the response of rare CFTR mutations to various modulators and treatment strategies. Recent work includes exploring organoid technology for theratyping applications and investigating the antiviral properties of CFTR inhibitors against SARS-CoV-2. His contributions to the field highlight innovative approaches to understanding and treating genetic respiratory diseases.

Articles (14)

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2024

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2024

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2024

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2023

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2022

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2022

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2022

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2022

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2022

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2022

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2022

Collaborators (7)

Alessandro Mosca

Free University of Bozen-Bolzano

ITALY

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Marcel Bijvelds

Erasmus University Rotterdam

NETHERLANDS

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Paola Lecca

Assistant Professor

Free University of Bozen-Bolzano

ITALY

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Giovanni Malerba

Associate Professor

University of Verona

ITALY

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Mario ROMANO

Full Professor of Laboratory Medicine

Università degli Studi Gabriele d'Annunzio Chieti e Pescara

ITALY

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Bruno Carpentieri

Free University of Bozen-Bolzano

ITALY

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Manuela Ferracin

Professor of Pathology

University of Bologna

ITALY

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Claudio Sorio

Research Interests

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Articles (14)

CFTR modulators response of S737F and T465N CFTR variants on patient-derived rectal organoids

Elexacaftor/tezacaftor/ivacaftor in people with cystic fibrosis and rare mutations

Functional rescue of CFTR in rectal organoids from patients carrying R334W variant by CFTR modulators and PDE4 inhibitor Roflumilast

Loss of CFTR Reverses Senescence Hallmarks in SARS-CoV-2 Infected Bronchial Epithelial Cells

Theratyping of the Rare CFTR Genotype A559T in Rectal Organoids and Nasal Cells Reveals a Relevant Response to Elexacaftor (VX-445) and Tezacaftor (VX-661) Combination

CFTR Modulators Rescue the Activity of CFTR in Colonoids Expressing the Complex Allele p.[R74W;V201M;D1270N]/dele22_24

CFTR Inhibitors Display In Vitro Antiviral Activity against SARS-CoV-2

Organoid Technology and Its Role for Theratyping Applications in Cystic Fibrosis

Ultrastructural Characterization of Human Bronchial Epithelial Cells during SARS-CoV-2 Infection: Morphological Comparison of Wild-Type and CFTR-Modified Cells

Achromobacter spp. Adaptation in Cystic Fibrosis Infection and Candidate Biomarkers of Antimicrobial Resistance

Gene Expression Landscape of Chronic Myeloid Leukemia K562 Cells Overexpressing the Tumor Suppressor Gene PTPRG

CFTR Modulation Reduces SARS-CoV-2 Infection in Human Bronchial Epithelial Cells

Theratyping of the Rare CFTR Variants E193K and R334W in Rectal Organoid-Derived Epithelial Monolayers

Description of PTPRG genetic variants identified in a cohort of Chronic Myeloid Leukemia patients and their ability to influence response to Tyrosine kinase Inhibitors

Collaborators (7)

Alessandro Mosca

Marcel Bijvelds

Paola Lecca

Giovanni Malerba

Mario ROMANO

Bruno Carpentieri

Manuela Ferracin

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