Céline Cruciani-Guglielmacci

Professor

Université Paris-Saclay

France

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Professor Céline Cruciani-Guglielmacci is a faculty member at Université de Paris, France. Her research focuses on metabolism, energy balance, and the interplay between dietary components and insulin resistance. Recent articles have explored topics such as the effects of GLP-1 analogs on bone material properties, adipose tissue macrophage plasticity in obesity, and the neural control of energy balance through brain lipid sensing.

Articles (20)

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2025

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2022

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2022

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2021

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2021

Collaborators (16)

Elina Akalestou

Lecturer

University of Leicester

UNITED KINGDOM

Céline Cruciani-Guglielmacci

Research Interests

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Articles (20)

The GLP-1 analog, exendin-4, improves bone material properties and strength through a central relay in ovariectomized mice

Preterm birth: A neuroinflammatory origin for metabolic diseases?

Whole-body deletion of Endospanin 1 protects from obesity-associated deleterious metabolic alterations

ABCG1 orchestrates adipose tissue macrophage plasticity and insulin resistance in obesity by rewiring saturated fatty acid pools

A multiorgan map of metabolic, signaling, and inflammatory pathways that coordinately control fasting glycemia in mice.

Brain lipid sensing and the neural control of energy balance.

Dietary docosahexaenoic acid (DHA) downregulates liver DHA synthesis by inhibiting eicosapentaenoic acid elongation.

Hepatic deletion of serine palmitoyl transferase 2 impairs ceramide/sphingomyelin balance, bile acids homeostasis and leads to liver damage in mice.

Antimicrobial protein REG3A regulates glucose homeostasis and insulin resistance in obese diabetic mice.

Interesterified palm oil promotes insulin resistance and altered insulin secretion and signaling in Swiss mice.

Fish oil minimises feed intake and improves insulin sensitivity in Zucker fa/fa rats.

Dopamine in the nucleus accumbens shell controls systemic glucose metabolism via the lateral hypothalamus and hepatic vagal innervation in rodents.

PIK3CA gain-of-function mutation in adipose tissue induces metabolic reprogramming with Warburg-like effect and severe endocrine disruption.

Mitofusins Mfn1 and Mfn2 Are Required to Preserve Glucose- but Not Incretin-Stimulated β-Cell Connectivity and Insulin Secretion.

Regenerating islet-derived protein 3α: A promising therapy for diabetes. Preliminary data in rodents and in humans.

ATGL-dependent white adipose tissue lipolysis controls hepatocyte PPARα activity.

Homocysteine Metabolism Pathway Is Involved in the Control of Glucose Homeostasis: A Cystathionine Beta Synthase Deficiency Study in Mouse.

Disruption of Pituitary Gonadotrope Activity in Male Rats After Short- or Long-Term High-Fat Diets Is Not Associated With Pituitary Inflammation.

Plasma triacylglycerols are biomarkers of β-cell function in mice and humans.

Sexually dimorphic roles for the type 2 diabetes-associated C2cd4b gene in murine glucose homeostasis.

Collaborators (16)

Elina Akalestou

Dominique Langin

Aida Martinez-Sanchez

Bryn Owen

Guillaume Mabilleau

Hervé Le Stunff

Alejandra Tomas

Nathalie Janel

MARIE LHOMME

Ola Hansson

Juliette Van Steenwinckel

Virginie Mattot

Carina Wagner

christophe magnan

Guillaume Canaud

Eleni Georgiadou

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