Clotilde Policar

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École Normale Supérieure

France

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About

Clotilde Policar is a Professor at Ecole Normale Supérieure in France. Her research areas include bioinorganic chemistry, the design and characterization of metal complexes, and the application of metal-based compounds in cellular models. She has recently published articles exploring topics such as anticancer prodrugs, mimetics of manganese superoxide dismutase, and innovative detection methods for metal speciation in cells.

Recent Grants

Grant: Close

MOBIDIC

Open Date: 2021-12-01

Close Date: 2024-01-01

Grant: Close

CATMAN — Catalytic Manganese-based anti-oxidants: an integrated approach from chemical design to bio-activity in cells — ANR 20-CE07-0039-01

Open Date: 2021-04-01

Close Date: 2024-04-01

Grant: Close

Imaging Mn Antioxidant in Cells: a Physical-Inorganic Cellular Chemistry Approach for Inflammatory Bowel Disease — DEI20151234413

Open Date: 2016-08-01

Close Date: 2019-07-01

Grant: Close

MAGIC Manganese Antioxidants delivered to Gut for Inflammation Control: Design and Evaluation — ANR-15-CE07-0027

Open Date: 2016-04-01

Close Date: 2021-06-01

Articles (16)

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2025

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2024

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2022

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2022

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2022

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2022

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2021

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2021

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2020

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2020

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2020

Collaborators (6)

Helene Bertrand

Associate Professor

Sorbonne Université

FRANCE

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Philippe SEKSIK

Prof

FRANCE

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Carole Nicco

Chief Scientific Officer

BELGIUM

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Cédric Tard

CNRS Associate Research Professor

Ecole Polytechnique

FRANCE

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Joëlle Vinh

Université PSL

FRANCE

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Michel Volovitch

Professeur émérite

Institut de Biologie de l'Ecole Normale Supérieure

FRANCE

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Clotilde Policar

Research Interests

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About

Recent Grants

Articles (16)

Inorganic chemical biology and metal complexes in cells: from the design of cellular models to evaluate antioxidant activity to the characterization of metal complexes in cells

A Targeted Redox‐Active Dual‐Action Pt(IV)‐Mn(II) Prodrug Displays Enhanced In Vivo Anticancer Activity

Bioinorganic Chemistry: A Field Where Biomimetism and Bioinspiration Are Central

Book Review

Deciphering the Metal Speciation in Low‐Molecular‐Weight Complexes by IMS‐MS: Application to the Detection of Manganese Superoxide Dismutase Mimics in Cell Lysates

Inertness of Superoxide Dismutase Mimics Mn(II) Complexes Based on an Open-Chain Ligand, Bioactivity, and Detection in Intestinal Epithelial Cells

A New Manganese Superoxide Dismutase Mimetic Improves Oxaliplatin-Induced Neuropathy and Global Tolerance in Mice

SOD mimics: From the tool box of the chemists to cellular studies

Cellular Detection of a Mitochondria Targeted Brominated Vinyl Triphenylamine Optical Probe (TP−Br) by X‐Ray Fluorescence Microscopy

Improvement of Peptidyl Copper Complexes Mimicking Catalase: A Subtle Balance between Thermodynamic Stability and Resistance towards H2O2 Degradation

Louis Pasteur dans l’œil du microscope

Rhenium carbonyl complexes bearing methylated triphenylphosphonium cations as antibody-free mitochondria trackers for X-ray fluorescence imaging

A di-Copper Peptidyl Complex Mimics the Activity of Catalase, a Key Antioxidant Metalloenzyme

Rational De Novo Design of a Cu Metalloenzyme for Superoxide Dismutation

Monitoring the Kinetics of the Cellular Uptake of a Metal Carbonyl Conjugated with a Lipidic Moiety in Living Cells Using Synchrotron Infrared Spectromicroscopy

An easy-to-implement combinatorial approach involving an activity-based assay for the discovery of a peptidyl copper complex mimicking superoxide dismutase

Collaborators (6)

Helene Bertrand

Philippe SEKSIK

Carole Nicco

Cédric Tard

Joëlle Vinh

Michel Volovitch

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