Craig J. McClain

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University of Louisville

United States

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Recent Grants

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Dietary Fat and Alcoholic Liver Disease

Open Date: 2016-10-01

Close Date: 2020-09-30

Grant: Close

Hepatobiology and Toxicology COBRE

Open Date: 2016-06-10

Close Date: 2021-03-31

Grant: Close

The Role of Nutrition in the Development/Progression of Alcohol-Induced Organ Injury

Open Date: 2016-05-15

Close Date: 2021-04-30

Grant: Close

Oxidized Metabolites of Linoleic Acid in Alcohol-induced Liver Injury

Open Date: 2014-09-01

Close Date: 2019-06-30

Grant: Close

Mechanisms for alcohol induced gut barrier dysfunction in ALD

Open Date: 2014-07-05

Close Date: 2019-06-30

Articles (21)

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University of Louisville

UNITED STATES

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Craig J. McClain

Research Interests

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Recent Grants

Articles (21)

Hepatocyte-Specific Transcriptional Responses to Liver-Targeted Delivery of a Soluble Epoxide Hydrolase Inhibitor in a Mouse Model of Alcohol-Associated Liver Disease

Chronic and Heavy Drinking, Nutrition Status, and Progression of Liver Injury Negatively Affect the Mortality Risk in Patients Suffering from Alcohol-Associated Hepatitis

Effects of soluble epoxide hydrolase inhibition on liver injury and gut microbiota in mice chronically fed ethanol

Urine Metabolites as Biomarkers and Metabolism Mechanism Studies of Alcohol-Associated Liver Disease

ACG Clinical Guideline: Malnutrition and Nutritional Recommendations in Liver Disease

Ileum Proteomics Identifies Distinct Pathways Associated with Different Dietary Doses of Copper–Fructose Interactions: Implications for the Gut–Liver Axis and MASLD

Intestine epithelial–specific hypoxia-inducible factor-1α overexpression ameliorates western diet–induced MASLD

The Modulatory Effects and Therapeutic Potential of Cannabidiol in the Gut

Hepatic Proteomic Changes Associated with Liver Injury Caused by Alcohol Consumption in Fpr2−/− Mice

Peripherally Restricted CB1 Receptor Inverse Agonist JD5037 Treatment Exacerbates Liver Injury in MDR2-Deficient Mice

Altered urinary tryptophan metabolites in alcohol‐associated liver disease

The Beneficial Effects of Lactobacillus GG Therapy on Liver and Drinking Assessments in Patients with Moderate Alcohol-Associated Hepatitis

Keratin 18‐M65: A biomarker for early‐stage alcohol‐associated liver disease

FGF21 Depletion Attenuates Colitis through Intestinal Epithelial IL-22-STAT3 Activation in Mice

Fpr2−/− Mice Developed Exacerbated Alcohol-Associated Liver Disease

Metabolic Analysis of Nucleosides/Bases in the Urine and Serum of Patients with Alcohol-Associated Liver Disease

Plasma Metabolomics Analysis of Polyvinyl Chloride Workers Identifies Altered Processes and Candidate Biomarkers for Hepatic Hemangiosarcoma and Its Development

Ileum Gene Expression in Response to Acute Systemic Inflammation in Mice Chronically Fed Ethanol: Beneficial Effects of Elevated Tissue n-3 PUFAs

cAMP Signaling in Pathobiology of Alcohol Associated Liver Disease

Soluble Epoxide Hydrolase Inhibition in Liver Diseases: A Review of Current Research and Knowledge Gaps

Fifteen Years of Gene Set Analysis for High-Throughput Genomic Data: A Review of Statistical Approaches and Future Challenges

Collaborators (6)

Xiang Zhang

MING SONG

Eugene Mueller

Carolyn Klinge

Bradford Hill

Vatsalya Vatsalya

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