Daisuke Miyoshi

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Japan

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About

Professor Daisuke Miyoshi is a faculty member at Konan Daigaku, Japan. His research focuses on the biophysical properties of nucleic acids, particularly in the areas of liquid-liquid phase separation and DNA G-quadruplex structures. Recent publications explore the effects of molecular crowding on i-motif DNA and the implications of cytosine methylation in nucleic acid topology. Professor Miyoshi's work significantly contributes to the understanding of RNA behavior in biological processes.

Recent Grants

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Creation of molecular targeted photodynamic therapy for quadruple helix structure of the cancer cell-specific mRNA

Open Date: 2016-04-01

Close Date: 2018-03-31

Grant: Close

Creation of molecular targeted photodynamic therapy for quadruple helix structure of the cancer cell-specific mRNA

Open Date: 2016-04-01

Close Date: 2018-03-31

Grant: Close

The construction of a gene expression artificial control system according to the three-way effect of DNA · histone Ozumoraito

Open Date: 2015-04-01

Close Date: 2018-03-31

Grant: Close

The construction of a gene expression artificial control system according to the three-way effect of DNA · histone Ozumoraito

Open Date: 2015-04-01

Close Date: 2018-03-31

Grant: Close

Construction of cell model experimental system using an osmotic pressure regulatory molecules and artificial polymer compound produced by the cells

Open Date: 2014-04-01

Close Date: 2016-03-31

Articles (19)

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2025

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2022

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2022

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2022

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2021

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2021

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2020

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2020

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2020

Collaborators (7)

Shu-ichi Nakano

Professor

Konan University

JAPAN

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Naoki Sugimoto

Konan University

JAPAN

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Takakazu Nakabayashi

Tohoku University

JAPAN

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Saki Matsumoto

Specially appointed assistant professor

Konan University

JAPAN

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Keiko Kawauchi

JAPAN

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Hiroaki Hirata

Kanazawa Institute of Technology

JAPAN

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Shinji Kajimoto

Associate Professor

Tohoku University

JAPAN

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Daisuke Miyoshi

Research Interests

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Contact this professor

About

Recent Grants

Articles (19)

Liquid‒liquid phase separation induced by i-motif DNA under molecular crowding conditions

Roles of Loop Region in Folding Kinetics and Transcription Inhibition of DNA G-Quadruplexes

Factors Affecting Liquid‐Liquid Phase Separation of RGG Peptides with DNA G‐Quadruplex

Front Cover: Factors Affecting Liquid‐Liquid Phase Separation of RGG Peptides with DNA G‐Quadruplex (ChemMedChem 2/2025)

The role of cytosine methylation in regulating the topology and liquid–liquid phase separation of DNA G-quadruplexes

Three- and four-stranded nucleic acid structures and their ligands

Quantitative Effects of the Loop Region on Topology, Thermodynamics, and Cation Binding of DNA G-quadruplexes

Bioinformatic Analysis of Actin-Binding Proteins in the Nucleolus During Heat Shock

NRAS DNA G-quadruplex-targeting molecules for sequence-selective enzyme inhibition

Quantification of the concentration in a droplet formed by liquid–liquid phase separation of G-quadruplex-forming RNA

Biomolecular Liquid–Liquid Phase Separation for Biotechnology

Controlling liquid–liquid phase separation of G-quadruplex-forming RNAs in a sequence-specific manner

Intramolecular G-quadruplex-hairpin loop structure competition of a GC-rich exon region in the TMPRSS2 gene

Significant structural change in human c-Myc promoter G-quadruplex upon peptide binding in potassium

Artificial turn-on riboswitch to control target gene expression using a wild-type riboswitch splicing mechanism

Combined Effects of Methylated Cytosine and Molecular Crowding on the Thermodynamic Stability of DNA Duplexes

Hydroxyl groups in cosolutes regulate the G-quadruplex topology of telomeric DNA

Photosensitizers Based on G-Quadruplex Ligand for Cancer Photodynamic Therapy

RNA phase separation–mediated direction of molecular trafficking under conditions of molecular crowding

Collaborators (7)

Shu-ichi Nakano

Naoki Sugimoto

Takakazu Nakabayashi

Saki Matsumoto

Keiko Kawauchi

Hiroaki Hirata

Shinji Kajimoto

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