Danchen Wu

Adjunct assistant professor

Queen's University

Canada

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Danchen Wu is an Adjunct Assistant Professor at Queen's University. His research primarily focuses on pulmonary arterial hypertension, mitochondrial metabolism, and the effects of mitochondrial dysfunction. Recent articles by Professor Wu highlight the roles of genetic variants, mitochondrial dynamics, and cell proliferation in relation to pulmonary health and disease.

Articles (13)

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2025

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2024

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2023

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2023

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2023

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2022

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2022

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2022

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2021

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2021

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2020

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2020

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2020

Collaborators (10)

Kimberly Dunham-Snary

Assistant Professor

Queen's University

CANADA

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Patricia Lima

Assistant Adjunct Professor

Queen's University

CANADA

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Sasha Prisco

Assistant Professor

University of Minnesota

UNITED STATES

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Sirio Dupont

Associate Professor

University of Padua

ITALY

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Anna Urciuolo

University of Padua

ITALY

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Willard W. Sharp

Associate Professor

University of Chicago

UNITED STATES

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Kurt Prins

University of Minnesota

UNITED STATES

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Gerald Evans

Professor

Queen's University

CANADA

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Soichi Shibuya

Associate Professor

Juntendo University

JAPAN

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Lian Tian

University Of Strathclyde

UNITED KINGDOM

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Danchen Wu

Research Interests

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Articles (13)

Germline and somatic variants in DNMT3A and other clonal haematopoiesis of indeterminate potential genes contribute to pulmonary arterial hypertension

Novel Drp1 GTPase Inhibitor, Drpitor1a: Efficacy in Pulmonary Hypertension

Electron Leak From the Mitochondrial Electron Transport Chain Complex I at Site I Q Is Crucial for Oxygen Sensing in Rabbit and Human Ductus Arteriosus

Acquired disorders of mitochondrial metabolism and dynamics in pulmonary arterial hypertension

Editorial: The effects of mitochondrial dysfunction on the cell cycle.

Mitochondrial fission links ECM mechanotransduction to metabolic redox homeostasis and metastatic chemotherapy resistance

Macrophage–NLRP3 Activation Promotes Right Ventricle Failure in Pulmonary Arterial Hypertension

SARS-CoV-2 mitochondriopathy in COVID-19 pneumonia exacerbates hypoxemia.

Oxygen sensing, mitochondrial biology and experimental therapeutics for pulmonary hypertension and cancer

PINK1-induced phosphorylation of mitofusin 2 at serine 442 causes its proteasomal degradation and promotes cell proliferation in lung cancer and pulmonary arterial hypertension

An epigenetic increase in mitochondrial fission by MiD49 and MiD51 regulates the cell cycle in cancer: Diagnostic and therapeutic implications

Clinical value of non-coding RNAs in cardiovascular, pulmonary, and muscle diseases

Epigenetic Metabolic Reprogramming of Right Ventricular Fibroblasts in Pulmonary Arterial Hypertension: A Pyruvate Dehydrogenase Kinase-Dependent Shift in Mitochondrial Metabolism Promotes Right Ventricular Fibrosis

Collaborators (10)

Kimberly Dunham-Snary

Patricia Lima

Sasha Prisco

Sirio Dupont

Anna Urciuolo

Willard W. Sharp

Kurt Prins

Gerald Evans

Soichi Shibuya

Lian Tian

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