Daniel JJ Carr

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Professor

University of Oklahoma Health Sciences Center

United States

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About

Daniel JJ Carr is a Professor at the University of Oklahoma Health Sciences Center in the United States. His research primarily focuses on immunological responses to herpes simplex virus, particularly in ocular infections. Recent articles highlight the role of complement in interferon responses and the development of live-attenuated vaccine candidates for HSV-1 and HSV-2.

Recent Grants

Grant: Close

Corneal Lymphatics & Adaptive Immunity

Open Date: 2010-12-01

Close Date: 2020-11-30

Grant: Close

The Neuroimmunology of Viral Infection

Open Date: 2003-04-01

Close Date: 2022-12-31

Articles (8)

Year:

2024

Year:

2022

Year:

2022

Year:

2022

Year:

2021

Year:

2021

Year:

2020

Year:

2020

Collaborators (2)

Edward Gershburg

Chief Technical Officer

Solaris Vaccines Inc

UNITED STATES

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Andrea Bertke

Associate Professor

Virginia Polytechnic Institute and State University

UNITED STATES

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Daniel JJ Carr

Research Interests

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About

Recent Grants

Articles (8)

Complement Suppresses the Initial Type 1 Interferon Response to Ocular Herpes Simplex Virus Type 1 Infection in Mice

HSV-1 0∆NLS vaccine elicits a robust B lymphocyte response and preserves vision without HSV-1 glycoprotein M or thymidine kinase recognition

Noncognate Signals Drive Enhanced Effector CD8 + T Cell Responses through an IFNAR1-Dependent Pathway after Infection with the Prototypic Vaccine, 0ΔNLS, against Herpes Simplex Virus 1

Tripartite-Motif 21 (TRIM21) Deficiency Results in a Modest Loss of Herpes Simplex Virus (HSV)-1 Surveillance in the Trigeminal Ganglia Following Cornea Infection

Assessment of Two Novel Live-Attenuated Vaccine Candidates for Herpes Simplex Virus 2 (HSV-2) in Guinea Pigs

The Durability of Vaccine Efficacy against Ocular HSV-1 Infection Using ICP0 Mutants 0∆NLS and 0∆RING Is Lost over Time

Herpes Simplex Virus 1 (HSV-1) 0ΔNLS Live-Attenuated Vaccine Protects against Ocular HSV-1 Infection in the Absence of Neutralizing Antibody in HSV-1 gB T Cell Receptor-Specific Transgenic Mice

Distinguishing Features of High- and Low-Dose Vaccine against Ocular HSV-1 Infection Correlates with Recognition of Specific HSV-1–Encoded Proteins

Collaborators (2)

Edward Gershburg

Andrea Bertke

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