Daniel Klionsky

Alexander G. Ruthven Professor of Life Sciences

University of Michigan

United States

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About

Daniel Klionsky is the Alexander G. Ruthven Professor of Life Sciences at the University of Michigan, USA. His research focuses on autophagy, particularly its role in cancer, mitochondrial dynamics, and stress response mechanisms. Recent publications include studies on the immune response in nasopharyngeal carcinoma and the biochemical investigation of autophagy-related proteins. He is also involved in exploring therapeutic applications of autophagy modulators in epilepsy and emotional homeostasis.

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Collaborators (6)

Baharia Mograbi

FRANCE

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Daolin Tang

University of Texas Southwestern Medical Center

UNITED STATES

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Paul Hofman

Université Côte d'Azur

FRANCE

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Marek Skoneczny

Institute of Biochemistry and Biophysics, Polish Academy of Sciences

POLAND

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Patrick Brest

Université Côte d'Azur

FRANCE

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Joanna Kamińska

Institute of Biochemistry and Biophysics, Polish Academy of Sciences

POLAND

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Daniel Klionsky

Research Interests

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About

Articles (30)

Autophagy inhibition in LGALS9-overexpressing nasopharyngeal carcinoma unleashes immune response

MoSec13 combined with MoGcn5b modulates MoAtg8 acetylation and regulates autophagy in Magnaporthe oryzae

V-ATPase-dependent induction of selective autophagy

PPA2 activates MTFP1-DNM1L fission signaling to govern mitochondrial proliferation and mitophagy

Biochemical investigation of LC3/GABARAP-ligand interaction as an important quality measure for LC3/GABARAP-targeting small molecules: addendum to the guidelines (4th edition)

Epilepsy and autophagy modulators: a therapeutic split

Coping with stress: the essential role of brain autophagy in emotional homeostasis

Npl3 is required for efficient autophagosome-vacuole fusion

Cancer-associated mutations in autophagy-related proteins analyzed in yeast and human cells

Mammalian nucleophagy: process and function

Macroautophagy/autophagy promotes resistance to KRASG12D-targeted therapy through glutathione synthesis

The interplay between probiotics and host autophagy: mechanisms of action and emerging insights

Why nuclease free water ruined my experiment (but at least it was free), or why the short dash matters

ATG14 and STX18: gatekeepers of lipid droplet degradation and the implications for disease modulation

The emerging significance of Vac8, a multi-purpose armadillo-repeat protein in yeast

Integrating bioengineering, super-resolution microscopy and mechanobiology in autophagy research: addendum to the guidelines (4th edition)

Pho81 is a novel regulator of pexophagy induced by phosphate starvation

A delicate decision between repair and degradation of damaged lysosomes

Defective autophagy and autophagy activators in myasthenia gravis: a rare entity and unusual scenario

Dysregulation of pancreatic β-cell autophagy and the risk of type 2 diabetes

Stability of Rad51 recombinase and persistence of Rad51 DNA repair foci depends on post-translational modifiers, ubiquitin and SUMO

GPX4 in cell death, autophagy, and disease

Should evidence of an autolysosomal de-acidification defect in Alzheimer and Parkinson diseases call for caution in prescribing chronic PPI and DMARD?

The interaction between autophagy, Helicobacter pylori, and gut microbiota in gastric carcinogenesis

The beneficial role of autophagy in multiple sclerosis: yes or no?

Autophagy is the key to making chronic wounds acute in skin wound healing

SPART links autophagy machinery and lipid droplets in motor neurons

CLU (clusterin) promotes mitophagic degradation of MSX2 through an AKT-DNM1L/Drp1 axis to maintain SOX2-mediated stemness in oral cancer stem cells

Copper metabolism in cell death and autophagy

Bruchpiloting synaptic connections: Egfr in autophagy-mediated neuronal circuit development

Collaborators (6)

Baharia Mograbi

Daolin Tang

Paul Hofman

Marek Skoneczny

Patrick Brest

Joanna Kamińska

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