Daniel Tyrrell

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Assistant Professor

The University of Alabama at Birmingham School of Medicine

United States

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About

Daniel Tyrrell is an Assistant Professor at The University of Alabama at Birmingham Heersink School of Medicine in the United States. His research interests focus on cardiovascular aging, immune cell characterization, and cellular senescence, as illustrated by his recent publications on atrial fibrillation, spectral flow cytometry, and the role of FGF receptors in the cystic fibrosis airway epithelium.

Recent Grants

Grant: Close

Cerebrovascular Mitochondrial Function in Aging and Ischemic Injury

Open Date: 2021-04-01

Close Date: 2023-03-31

Grant: Close

Immune Basis of how Inflammation, Atherosclerosis, and Aging Enhance Atrial Fibrillation

Open Date: 2017-12-28

Close Date: 2020-07-27

Articles (18)

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2025

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2020

Collaborators (3)

Alexi Vasbinder

Assistant Professor

University of Washington

UNITED STATES

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Daniel R. Goldstein

UNITED STATES

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Morgan Salmon

University of Michigan

UNITED STATES

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Daniel Tyrrell

Research Interests

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About

Recent Grants

Articles (18)

Paradoxical SERCA2a Dysregulation Contributes to Atrial Fibrillation in a Model of Diet-Induced Obesity

CAFE: an integrated web app for high-dimensional analysis and visualization in spectral flow cytometry

FGF receptors mediate cellular senescence in the cystic fibrosis airway epithelium

Publisher Correction: Clonally expanded memory CD8+ T cells accumulate in atherosclerotic plaques and are pro-atherogenic in aged mice

Cardiovascular aging: spotlight on mitochondria

Analysis of NIH K99/R00 awards and the career progression of awardees

Analysis of NIH K99/R00 awards and the career progression of awardees

Development of a Spectral Flow Cytometry Analysis Pipeline for High-dimensional Immune Cell Characterization

Age‐associated adipose tissue inflammation promotes monocyte chemotaxis and enhances atherosclerosis

Itaconate suppresses atherosclerosis by activating a Nrf2-dependent antiinflammatory response in macrophages in mice

Clonally expanded memory CD8+ T cells accumulate in atherosclerotic plaques and are pro-atherogenic in aged mice

Increased soluble urokinase plasminogen activator levels modulate monocyte function to promote atherosclerosis

Aging Alters the Aortic Proteome in Health and Thoracic Aortic Aneurysm.

Aging Alters the Aortic Proteome in Health and Thoracic Aortic Aneurysm

Aging Impairs Mitochondrial Function and Mitophagy and Elevates Interleukin 6 Within the Cerebral Vasculature.

Aging Impairs Mitochondrial Function and Mitophagy and Elevates Interleukin 6 Within the Cerebral Vasculature

Ageing and atherosclerosis: vascular intrinsic and extrinsic factors and potential role of IL-6.

Age-Associated Mitochondrial Dysfunction Accelerates Atherogenesis

Collaborators (3)

Alexi Vasbinder

Daniel R. Goldstein

Morgan Salmon

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