Danuta Drozdowska

asssistant professor

Medical University

Poland

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About

Danuta Drozdowska is an Assistant Professor at the Medical University in Poland. Her research focuses on the synthesis and biological activity of novel compounds, particularly in the context of human dihydrofolate reductase inhibitors, antimicrobial agents, and multi-targeted compounds. Recent articles highlight her work on benzamide derivatives and s-triazine core compounds, targeting various enzyme activities relevant to cancer treatment and bacterial DNA gyrases.

Articles (9)

Year:

2024

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2023

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2023

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2022

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2021

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2021

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2021

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2020

Year:

2020

Collaborators (3)

Artur Ratkiewicz

Associate professor

Bialystok University of Technology

POLAND

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Beata Kolesinska

Lodz University of Technology

POLAND

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Anna Tankiewicz-Kwedlo

Assistant Professor

Medical University of Białystok

POLAND

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Danuta Drozdowska

Research Interests

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Articles (9)

Benzamide Trimethoprim Derivatives as Human Dihydrofolate Reductase Inhibitors—Molecular Modeling and In Vitro Activity Study

s-Triazine Derivatives Functionalized with Alkylating 2-Chloroethylamine Fragments as Promising Antimicrobial Agents: Inhibition of Bacterial DNA Gyrases, Molecular Docking Studies, and Antibacterial and Antifungal Activity

New Benzamides as Multi-Targeted Compounds: A Study on Synthesis, AChE and BACE1 Inhibitory Activity and Molecular Docking

Recent Advances in the Biological Activity of s-Triazine Core Compounds

1,3,5-Triazine Nitrogen Mustards with Different Peptide Group as Innovative Candidates for AChE and BACE1 Inhibitors

Synthesis, Biological Activity, and Molecular Dynamics Study of Novel Series of a Trimethoprim Analogs as Multi-Targeted Compounds: Dihydrofolate Reductase (DHFR) Inhibitors and DNA-Binding Agents

Recent Design and Structure-Activity Relationship Studies on the Modifications of DHFR Inhibitors as Anticancer Agents

Synthesis and cellular effects of novel 1,3,5-triazine derivatives in DLD and Ht-29 human colon cancer cell lines

Trimethoprim and other nonclassical antifolates an excellent template for searching modifications of dihydrofolate reductase enzyme inhibitors

Collaborators (3)

Artur Ratkiewicz

Beata Kolesinska

Anna Tankiewicz-Kwedlo

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