Danxin Wang

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Associate Professor

University of Florida

United States

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About

Danxin Wang is an Associate Professor at the University of Florida, United States. His research areas encompass pharmacogenomics and molecular biology, focusing on gene expression regulation and its implications in human liver samples. Recent publications include studies on genetic variants influencing CYP2C9 and UGT1A1 expression, as well as the role of circulating microRNAs in cardiovascular events related to multiple myeloma and hypertension.

Recent Grants

Grant: Close

Expression genetics of pharmacogenes

Open Date: 2021-04-01

Close Date: 2026-01-31

Grant: Close

Translational candidate gene studies of simvastatin-induced myopathy in African Americans

Open Date: 2017-10-01

Close Date: 2022-09-01

Grant: Close

Expression Genetics of CYP3A Drug Metabolizing Enzymes

Open Date: 2017-04-01

Close Date: 2022-03-31

Grant: Close

Genetic determinants of ACEI prodrug activation

Open Date: 2016-01-01

Close Date: 2021-01-01

Grant: Close

Pharmacogenetics of sulfamethoxazole in HIV/AIDS patients

Open Date: 2008-06-01

Close Date: 2011-05-31

Articles (15)

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2025

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2025

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2024

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2024

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2024

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2022

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2022

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2022

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2021

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2021

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2021

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2021

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2021

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2021

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2020

Collaborators (6)

Caitrin McDonough

Assistant Professor

University of Florida

UNITED STATES

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Yan Gong

UNITED STATES

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Reginald Frye

Professor and Chair

University of Florida College of Pharmacy

UNITED STATES

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Julie A. Johnson

UNITED STATES

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John G. Gums

UNITED STATES

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Lexie Holliday

University of Florida

UNITED STATES

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Danxin Wang

Research Interests

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About

Recent Grants

Articles (15)

The Association Between Promoter Tandem Repeat Polymorphism (pVNTR) and CYP2C9 Gene Expression in Human Liver Samples

Association Between UGT1A1 mRNA Expression and Cis-Acting Genetic Variants and Trans-Acting Transcriptional Regulators in Human Liver Samples

Differential Expression of Circulating miRNAs and Carfilzomib-Related Cardiovascular Adverse Events in Patients with Multiple Myeloma

Circulating microRNA Biomarkers of Thiazide Response in Hypertension

DNA Methylation in the CYP3A Distal Regulatory Region (DRR) Is Associated with the Expression of CYP3A5 and CYP3A7 in Human Liver Samples

Transcription Factors and ncRNAs Associated with <i>CYP3A</i> Expression in Human Liver and Small Intestine Assessed with Weighted Gene Co-Expression Network Analysis

PharmVar GeneFocus: CYP3A5.

Regulation of CYP3A4 and CYP3A5 by a lncRNA: a potential underlying mechanism explaining the association between CYP3A4*1G and CYP3A metabolism.

Transcriptional Regulation of Carboxylesterase 1 in Human Liver: Role of the Nuclear Receptor Subfamily 1 Group H Member 3 and Its Splice Isoforms.

Genome-wide Association Study Identified Chromosome 8 Locus Associated with Medication-Related Osteonecrosis of the Jaw.

Cytochrome P450 3A4 (CYP3A4) protein quantification using capillary western blot technology and total protein normalization.

Co-expression of drug metabolizing cytochrome P450 enzymes and estrogen receptor alpha (ESR1) in human liver: racial differences and the regulatory role of ESR1.

Functional CYP3A variants affecting tacrolimus trough blood concentrations in Chinese renal transplant recipients.

ESR1 ChIP-Seq Identifies Distinct Ligand-Free ESR1 Genomic Binding Sites in Human Hepatocytes and Liver Tissue.

Examination of Metoprolol Pharmacokinetics and Pharmacodynamics Across CYP2D6 Genotype-Derived Activity Scores.

Collaborators (6)

Caitrin McDonough

Yan Gong

Reginald Frye

Julie A. Johnson

John G. Gums

Lexie Holliday

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