Darren Fayne

Trinity College Dublin

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Articles (18)

Collaborators (4)

Clive Williams

Professor emeritus

Trinity College Dublin

Oliviero Gobbo

Trinity College Dublin

Anthony McElligott

Assistant Professor in Molecular Haematology

Trinity College Dublin

Niamh M. O'Boyle

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Darren Fayne

Research Interests

Explore related searches

Contact this professor

Articles (18)

Collaborators (4)

Clive Williams

Oliviero Gobbo

Anthony McElligott

Niamh M. O'Boyle

Make your next move.

Darren Fayne

Research Interests

Explore related searches

Contact this professor

Articles (18)

The Use of Computational Approaches to Design Nanodelivery Systems

Synthesis, Computational Studies, and Structural Analysis of 1-(3,5-Dimethoxyphenyl)azetidin-2-ones with Antiproliferative Activity in Breast Cancer and Chemoresistant Colon Cancer

Correction: Malebari et al. Synthesis and Antiproliferative Evaluation of 3-Chloroazetidin-2-ones with Antimitotic Activity: Heterocyclic Bridged Analogues of Combretastatin A-4. Pharmaceuticals 2021, 14, 1119

Correction: Wang et al. Antiproliferative and Tubulin-Destabilising Effects of 3-(Prop-1-en-2-yl)azetidin-2-Ones and Related Compounds in MCF-7 and MDA-MB-231 Breast Cancer Cells. Pharmaceuticals 2023, 16, 1000

(E)-1-(3-(3-Hydroxy-4-Methoxyphenyl)-1-(3,4,5-Trimethoxyphenyl)allyl)-1H-1,2,4-Triazole and Related Compounds: Their Synthesis and Biological Evaluation as Novel Antimitotic Agents Targeting Breast Cancer

MERS-CoV-nsp5 expression in human epithelial BEAS 2b cells attenuates type I interferon production by inhibiting IRF3 nuclear translocation

Respiratory syncytial virus NS1 inhibits anti-viral Interferon-α-induced JAK/STAT signaling, by limiting the nuclear translocation of STAT1

Synthesis and Biochemical Evaluation of Ethanoanthracenes and Related Compounds: Antiproliferative and Pro-Apoptotic Effects in Chronic Lymphocytic Leukemia (CLL)

DataPype: A Fully Automated Unified Software Platform for Computer-Aided Drug Design

Genetic conservation across SARS-CoV-2 non-structural proteins – Insights into possible targets for treatment of future viral outbreaks

Antiproliferative and Tubulin-Destabilising Effects of 3-(Prop-1-en-2-yl)azetidin-2-Ones and Related Compounds in MCF-7 and MDA-MB-231 Breast Cancer Cells

Mapping of Protein Binding Sites using clustering algorithms - Development of a pharmacophore based drug discovery tool

Synthesis and Antiproliferative Evaluation of 3-Chloroazetidin-2-ones with Antimitotic Activity: Heterocyclic Bridged Analogues of Combretastatin A-4

Synthesis and Biological Evaluation of 1-(Diarylmethyl)-1H-1,2,4-triazoles and 1-(Diarylmethyl)-1H-imidazoles as a Novel Class of Anti-Mitotic Agent for Activity in Breast Cancer

Design, Synthesis and Biochemical Evaluation of Novel Ethanoanthracenes and Related Compounds to Target Burkitt's Lymphoma

Repurposing drugs for treatment of SARS-CoV-2 infection: computational design insights into mechanisms of action.

Synthesis, Anti-proliferative Activity, and Molecular Docking Study of New Series of 1,3-5-Triazine Schiff Base Derivatives.

β-Lactams with antiproliferative and antiapoptotic activity in breast and chemoresistant colon cancer cells.

Collaborators (4)

Clive Williams

Oliviero Gobbo

Anthony McElligott

Niamh M. O'Boyle

Make your next move.