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David Carling

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Group Leader

MRC London Institute of Medical Sciences

United Kingdom

Research Interests

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Professors in United Kingdom Professors in Biochemistry Biochemistry professors in United Kingdom

Recent Grants

Grant: Close

High content analysis of 3-D cell cultures with multidimensional fluorescence imaging

Open Date: 2015-05-31

Close Date: 2017-07-30

Grant: Close

Imaging cellular structure and function beyond the diffraction limit

Open Date: 2013-02-13

Close Date: 2017-08-11

Grant: Close

Biological Atlas of Insulin Resistance (BAIR).

Open Date: 2002-07-01

Close Date: 2009-12-31

Grant: Close

Cellular Stress

Open Date: 1994-03-31

Close Date:

Articles (20)

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2023

Collaborators (15)

Hannah Maude

Research Associate

Imperial College London

UNITED KINGDOM

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Bernard Khoo

University College London

UNITED KINGDOM

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Brijesh Kumar Singh

Assistant Professor

Duke-NUS Medical School

SINGAPORE

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Lara Menzies

Honorary Associate Professor

University College London

UNITED KINGDOM

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Craig Beall

Senior Lecturer

University of Exeter

UNITED KINGDOM

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Ian Salt

Reader

University of Glasgow

UNITED KINGDOM

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Tricia Tan

Professor of Metabolic Medicine and Endocrinology

Imperial College London

UNITED KINGDOM

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Alice Pollard

Imperial College London

UNITED KINGDOM

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Santiago Vernia

Group Leader

Consejo Superior de Investigaciones Cientificas

SPAIN

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Gavin Bewick

King’s College London

UNITED KINGDOM

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Nazila Kamaly

Associate Professor/Reader

Imperial College London

UNITED KINGDOM

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Robert Goldin

Imperial College London

UNITED KINGDOM

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Alice Adriaenssens

University College London

UNITED KINGDOM

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Kate L. J. Ellacott

Associate Pro-Vice-Chancellor (Education)

University of Exeter Medical School

UNITED KINGDOM

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David Rueda

Professor

Imperial College London

UNITED KINGDOM

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ApplyKite TwinLearns as you apply

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David Carling

Research Interests

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Recent Grants

Articles (20)

PGC1α expression using targeted redox-responsive nanogels protects against prostate cancer in vivo

Binding of 14-3-3 stabilises recombinant AMPKγ2-containing complexes

High-throughput proteomics sample preparation using a 96-channel pipettor and magnetic pin device

Hypoglycaemic stimulation of macrophage cytokine release is suppressed by AMP‐activated protein kinase activation

Precise intracellular uptake and endosomal release of diverse functional mRNA payloads via glutathione-responsive nanogels

High-throughput behavioural phenotyping of 25 C. elegans disease models including patient-specific mutations.

Spatial lipidomics reveals sphingolipid metabolism as anti-fibrotic target in the liver.

Oligodendrocyte precursor cell-specific blocking of low-glucose-induced activation of AMPK ensures myelination and remyelination

Chronic GIPR agonism results in pancreatic islet GIPR functional desensitisation

Dietary Protein Defends Lean Mass and Maintains the Metabolic Benefits of Glucagon Receptor Agonism in Mice

Inhibition of IL-11 signalling extends mammalian healthspan and lifespan

A special issue of Essays in Biochemistry on AMPK and AMPK-related kinases

AMPK activation suppresses leptin expression independently of adipogenesis in primary murine adipocytes.

Interleukin 11 therapy causes acute left ventricular dysfunction.

Chronic treatment with glucagon-like peptide-1 and glucagon receptor co-agonist causes weight loss-independent improvements in hepatic steatosis in mice with diet-induced obesity

Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase (Expression of Concern of Vol 415, Pg 339, 2002)

Correction: The CDK7 inhibitor CT7001 (Samuraciclib) targets proliferation pathways to inhibit advanced prostate cancer

Sleeve gastrectomy causes weight‐loss independent improvements in hepatic steatosis

The CDK7 inhibitor CT7001 (Samuraciclib) targets proliferation pathways to inhibit advanced prostate cancer

ENDOTHELIAL INFLAMMAGING AND MITOCHONDRIAL DYSFUNCTION IN THE ANTIPHOSPHOLIPID SYNDROME

Collaborators (15)

Hannah Maude

Bernard Khoo

Brijesh Kumar Singh

Lara Menzies

Craig Beall

Ian Salt

Tricia Tan

Alice Pollard

Santiago Vernia

Gavin Bewick

Nazila Kamaly

Robert Goldin

Alice Adriaenssens

Kate L. J. Ellacott

David Rueda

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