David Eisenberg

UCLA Life Sciences

United States

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Articles (11)

Year:

2023

Year:

2022

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2022

Year:

2022

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2021

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2021

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2021

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2020

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2020

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2020

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2020

Collaborators (3)

smriti sangwan

University of California, San Francisco

UNITED STATES

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Lorena Saelices Gomez

Assistant Professor

University of Texas Southwestern Medical Center

UNITED STATES

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Lukasz Salwinski

University of California, Los Angeles

UNITED STATES

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David Eisenberg

Research Interests

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Articles (11)

Fibril structures of TFG protein mutants validate the identification of TFG as a disease-related amyloid protein by the IMPAcT method

De novo designed protein inhibitors of amyloid aggregation and seeding

Identifying amyloid-related diseases by mapping mutations in low-complexity protein domains to pathologies

Cryo-EM structure of RNA-induced tau fibrils reveals a small C-terminal core that may nucleate fibril formation

Cryo-EM structures of hIAPP fibrils seeded by patient-extracted fibrils reveal new polymorphs and conserved fibril cores

Prevalence and species distribution of the low-complexity, amyloid-like, reversible, kinked segment structural motif in amyloid-like fibrils

Intrinsic electronic conductivity of individual atomically resolved amyloid crystals reveals micrometer-long hole hopping via tyrosines

Inhibition of synucleinopathic seeding by rationally designed inhibitors

CryoEM structure of the low-complexity domain of hnRNPA2 and its conversion to pathogenic amyloid

Cryo-EM structure and inhibitor design of human IAPP (amylin) fibrils

Cryo-EM structure of a human prion fibril with a hydrophobic, protease-resistant core

Collaborators (3)

smriti sangwan

Lorena Saelices Gomez

Lukasz Salwinski

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