David Gordon

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Associate Professor

Iowa State University

United States

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About

David Gordon is an Associate Professor at the University of Iowa in the United States. His research primarily focuses on Ewing sarcoma and its associated cellular mechanisms, along with studies in acute lymphoblastic leukemia and various tumor types. Recent publications include works on histone deacetylase inhibitors, activator protein signaling, and preclinical drug efficacy, contributing to the understanding of cancer biology and treatment strategies.

Recent Grants

Grant: Close

Gene expression signature based screening in Ewing sarcoma

Open Date: 2018-02-02

Close Date: 2023-01-31

Grant: Close

Trisomy 8 in Hematopoiesis and Myeloid Leukemia

Open Date: 2011-07-01

Close Date: 2016-06-30

Articles (14)

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2025

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2024

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2023

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2023

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2022

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2022

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2022

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2020

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2020

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2020

Collaborators (5)

Dawn Quelle

Professor

Iowa State University

UNITED STATES

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Meng Wu

Ohio State University

UNITED STATES

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Erica Carlisle

UNITED STATES

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Varun Monga

Clinical Associate Professor

University of California San Francisco Medical Center

UNITED STATES

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Peter M. Gordon

UNITED STATES

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David Gordon

Research Interests

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About

Recent Grants

Articles (14)

Histone Deacetylase Inhibitors Target DNA Replication Regulators and Replication Stress in Ewing Sarcoma Cells

EWS-FLI1 and Activator Protein-1 (AP-1) Reciprocally Regulate Extracellular-Matrix Proteins in Ewing sarcoma Cells

Activator Protein-1 (AP-1) Signaling Inhibits the Growth of Ewing Sarcoma Cells in Response to DNA Replication Stress

Cutaneous Metastasis of Alveolar Rhabdomyosarcoma in a Child.

Inhibitor of DNA binding 2 (ID2) regulates the expression of developmental genes and tumorigenesis in ewing sarcoma

Augmenting chemotherapy with low-dose decitabine through an immune-independent mechanism

Disruption of dNTP homeostasis by ribonucleotide reductase hyperactivation overcomes AML differentiation blockade.

Oncogenic RABL6A promotes NF1-associated MPNST progression in vivo.

Preclinical efficacy of prexasertib in acute lymphoblastic leukemia

The translational repressor 4E-BP1 regulates RRM2 levels and functions as a tumor suppressor in Ewing sarcoma tumors

Thoracic Sertoli-Leydig cell tumor: An alternative type of pleuropulmonary blastoma associated with DICER1 variation.

Eltrombopag inhibits the proliferation of Ewing sarcoma cells via iron chelation and impaired DNA replication

CDKs in Sarcoma: Mediators of Disease and Emerging Therapeutic Targets

Inhibition of the ATR–CHK1 Pathway in Ewing Sarcoma Cells Causes DNA Damage and Apoptosis via the CDK2-Mediated Degradation of RRM2

Collaborators (5)

Dawn Quelle

Meng Wu

Erica Carlisle

Varun Monga

Peter M. Gordon

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